| Gene Symbol | SLC12A2 |
|---|---|
| Entrez Gene | 6558 |
| Alt Symbol | BSC, BSC2, NKCC1, PPP1R141 |
| Species | Human |
| Gene Type | protein-coding |
| Description | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| Other Description | basolateral Na-K-Cl symporter|bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1|protein phosphatase 1, regulatory subunit 141|solute carrier family 12 (sodium/potassium/chloride transporters), member 2|solute carrier family 12 member 2 |
| Swissprots | Q8N713 Q8WWH7 P55011 |
| Accessions | EAW62392 EAW62393 EAW62394 P55011 AA425438 AA425619 AA843086 AB209192 BAD92429 AF439152 AAL32454 AI493213 AK025062 AV708692 AY280459 AAP33906 BC033003 BC144221 AAI44222 BC146839 AAI46840 BM978607 U30246 AAC50561 Z36839 XM_011543588 XP_011541890 NM_001046 NP_001037 NM_001256461 NP_001243390 NR_046207 |
| Function | Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume. |
| Subcellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed in many tissues. |
| Top Pathways | Vibrio cholerae infection, Salivary secretion, Pancreatic secretion |