B3GAT1

Gene Symbol B3GAT1
Entrez Gene 27087
Alt Symbol CD57, GLCATP, GLCUATP, HNK1, LEU7, NK-1, NK1
Species Human
Gene Type protein-coding
Description beta-1,3-glucuronyltransferase 1
Other Description LEU7 antigen|UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase|galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1|glcUAT-P|glucuronosyltransferase P
Swissprots Q96FS7 Q9P2W7
Accessions Q9P2W7 AB029396 BAA96077 AF131769 AK299637 BAH13084 AL834455 CAD39115 BC010466 AAH10466 CR457098 CAG33379 DQ893324 ABM84250 DQ895278 ABM86204 DQ896640 ABM87639 XM_005271506 XP_005271563 XM_005271508 XP_005271565 XM_011542751 XP_011541053 XM_011542752 XP_011541054 XM_011542753 XP_011541055 XM_011542754 XP_011541056 XM_011542755 XP_011541057 NM_018644 NP_061114 NM_054025 NP_473366
Function Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity). {ECO:0000250}.
Subcellular Location Golgi apparatus membrane; Single-pass type II membrane protein.
Tissue Specificity Mainly expressed in the brain.
Top Pathways Other types of O-glycan biosynthesis

CD57 (NK-1) - sc-6261 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD57 (NK-1): sc-6261. Immunoperoxidase staining of formalin-fixed, paraffin-embedded normal human lymph node at high magnification showing membrane staining.

CD57 (V-18) - sc-49197 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD57 (HNK-1) - sc-81633 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD57 (HNK-1): sc-81633. Western blot analysis of CD57 expression in CCRF-CEM whole cell lysate.

CD57 (E-12) - sc-49195 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD57 (HCD57) - sc-53669 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD57 (HCD57): sc-53669. Indirect FCM analysis of human peripheral blood leukocytes stained with CD57 (HCD57), followed by PE-conjugated goat anti-mouse IgM: sc-3768. Quadrant markers were set based on the isotype control, normal mouse IgM: sc-3881.

Anti-CD57 antibody - ab199156 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling CD57 with ab199156 at 1/40 dilution.

Anti-CD57 antibody - ab166942 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
All lanes : Anti-CD57 antibody (ab166942) at 0.1 µg/mlLane 1 : Human brain (frontal cortex) lysates in RIPA bufferLane 2 : Human brain (frontal cortex) lysates in RIPA buffer with blocking peptideLysates/proteins at 35 µg per lane.developed using the ECL technique

Anti-CD57 antibody - ab93482 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD57 antibody (ab93482) at 1/1000 dilutionLane 1 : SGC cell lysate at 40 µgLane 2 : SGC cell lysate at 40 µgLane 3 : Mouse liver lysate at 78 µgLane 4 : Mouse brain lysate at 84 µgLane 5 : Mouse brain lysate at 84 µg

Anti-CD57 antibody - ab103188 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CD57 antibody (ab103188) at 1/100 dilution + K562 cell lysate at 35 µg

Anti-CD57 antibody [B321 (NK-1)] - ab134236 from Abcam

Prices $372.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone B321 (NK-1)

Anti-CD57 antibody [HNK-1/ Leu-7] - ab187274 from Abcam

Prices $378.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone HNK-1/ Leu-7
Immunohistochemical staining of formalin-fixed paraffin-embedded Human tonsil tissue labeling CD57 with ab187274 at 1/50 dilution.

Anti-CD57 antibody [NK-1] - ab25629 from Abcam

Prices $373.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone NK-1

Anti-CD57 antibody [NK-1] (Biotin) - ab25614 from Abcam

Prices $372.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone NK-1

Anti-CD57 antibody [NK-1] (FITC) - ab25605 from Abcam

Prices $372.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone NK-1

Anti-CD57 antibody [NK-1] (PE/Cy5®) - ab25445 from Abcam

Prices $189.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone NK-1

Anti-CD57 antibody [NK-1] (Phycoerythrin) - ab25577 from Abcam

Prices $187.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone NK-1

Anti-CD57 antibody [NK1], prediluted - ab82749 from Abcam

Prices $376.00
Sizes 6 ml
Host Mouse
Clonality Monoclonal
Clone NK1
ICC/IF image of ab82749 stained U2OS cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab82749 at Undiluted (Used Neat) overnight at +4°C. The secondary antibody (pseudo-colored green) was Dylight® 488 goat anti- mouse (ab98674) IgM preadsorbed, used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1h at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-CD57 antibody [SPM129], prediluted - ab53653 from Abcam

Prices $376.00
Sizes 7 ml
Host Mouse
Clonality Monoclonal
Clone SPM129
ab53653 used neat staining CD57 in Human Tonsil by Immunohistochemistry, Formalin-fixed, Paraffin embedded tissue.

Anti-CD57 antibody [TB01] - ab33273 from Abcam

Prices $373.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone TB01

Anti-CD57 antibody [TB01 (TBO1)] - Low endotoxin, Azide free - ab185794 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone TB01 (TBO1)

Anti-CD57 antibody [VC1.1] - ab19783 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone VC1.1

Anti-CD57 / HNK1 Antibody (clone 6-13-19-1) - LS-C123075 from LifeSpan Bioscience

Prices $375.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone 6-13-19-1

Anti-CD57 / HNK1 Antibody (clone NK-1, Biotin) - LS-C134507 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone NK-1

Anti-CD57 / HNK1 Antibody (clone NK-1, FITC) - LS-C134508 from LifeSpan Bioscience

Prices $345.00
Sizes 120 tst
Host Mouse
Clonality Monoclonal
Clone NK-1

Anti-CD57 / HNK1 Antibody (clone NK-1, Azide-free) - LS-C134509 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone NK-1
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