Gene Symbol |
TBX21
|
Entrez Gene |
30009
|
Alt Symbol |
T-PET, T-bet, TBET, TBLYM
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
T-box 21
|
Other Description |
T-box expressed in T cells|T-box protein 21|T-box transcription factor TBX21|T-cell-specific T-box transcription factor T-bet|transcription factor TBLYM
|
Swissprots |
Q9UL17
|
Accessions |
CAY39299 CAY39301 EAW94804 Q9UL17 AF093098 AAF00055 AF241243 AAF61243 AK223634 BAD97354 BC039739 AAH39739 XM_011524698 XP_011523000 XM_011524699 XP_011523001 NM_013351 NP_037483
|
Function |
Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs.
|
Subcellular Location |
Nucleus.
|
Tissue Specificity |
T-cell specific.
|
Top Pathways |
Inflammatory bowel disease (IBD)
|