Gene Symbol | TBX21 |
---|---|
Entrez Gene | 30009 |
Alt Symbol | T-PET, T-bet, TBET, TBLYM |
Species | Human |
Gene Type | protein-coding |
Description | T-box 21 |
Other Description | T-box expressed in T cells|T-box protein 21|T-box transcription factor TBX21|T-cell-specific T-box transcription factor T-bet|transcription factor TBLYM |
Swissprots | Q9UL17 |
Accessions | CAY39299 CAY39301 EAW94804 Q9UL17 AF093098 AAF00055 AF241243 AAF61243 AK223634 BAD97354 BC039739 AAH39739 XM_011524698 XP_011523000 XM_011524699 XP_011523001 NM_013351 NP_037483 |
Function | Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs. |
Subcellular Location | Nucleus. |
Tissue Specificity | T-cell specific. |
Top Pathways | Inflammatory bowel disease (IBD) |
T-bet CRISPR/Cas9 KO Plasmid (h) - sc-400480 from Santa Cruz Biotechnology
|
||||||||
T-bet HDR Plasmid (h) - sc-400480-HDR from Santa Cruz Biotechnology
|
||||||||
T-bet Double Nickase Plasmid (h) - sc-400480-NIC from Santa Cruz Biotechnology
|
||||||||
T-bet Double Nickase Plasmid (h2) - sc-400480-NIC-2 from Santa Cruz Biotechnology
|
||||||||
T-bet CRISPR Activation Plasmid (h) - sc-400480-ACT from Santa Cruz Biotechnology
|
||||||||
T-bet CRISPR Activation Plasmid (h2) - sc-400480-ACT-2 from Santa Cruz Biotechnology
|
||||||||
T-bet Lentiviral Activation Particles (h) - sc-400480-LAC from Santa Cruz Biotechnology
|
||||||||
T-bet Lentiviral Activation Particles (h2) - sc-400480-LAC-2 from Santa Cruz Biotechnology
|
||||||||
T-bet siRNA (h) - sc-36598 from Santa Cruz Biotechnology
|
||||||||
T-bet shRNA Plasmid (h) - sc-36598-SH from Santa Cruz Biotechnology
|
||||||||
T-bet shRNA (h) Lentiviral Particles - sc-36598-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU137321 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN21110 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21110 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR07359 from Sigma-Aldrich
|
||||||||
TBX21 siRNA (Human) - CRH9331 from Cohesion Biosciences
|
||||||||
T-bet/TBX21 RNAi - H00030009-R01 from Novus Biologicals
|
||||||||
TBX21 - MBS827542 from MyBioSource
|
||||||||
T-bet siRNA (r) - sc-270589 from Santa Cruz Biotechnology
|
||||||||
T-bet shRNA Plasmid (r) - sc-270589-SH from Santa Cruz Biotechnology
|
||||||||
T-bet shRNA (r) Lentiviral Particles - sc-270589-V from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human TBX21 (NM_013351.1) - SHH424416 from Creative biogene
|
||||||||
TBX21 shRNA Plasmid (Human) - CHH9331 from Cohesion Biosciences
|
||||||||
TBX21 miRNA 3'UTR clone - MiUTR1H-10244 from Creative biogene
|