Gene Symbol | CEACAM3 |
---|---|
Entrez Gene | 1084 |
Alt Symbol | CD66D, CEA, CGM1, W264, W282 |
Species | Human |
Gene Type | protein-coding |
Description | carcinoembryonic antigen-related cell adhesion molecule 3 |
Other Description | CD66d antigen|carcinoembryonic antigen CGM1|carcinoembryonic antigen gene family member 1|nonspecific cross-reacting antigen |
Swissprots | Q3KPH9 G5E978 P40198 |
Accessions | AAA51965 CAA34473 EAW57062 EAW57063 EAW57064 EAW57065 P40198 AK298694 BAH12850 BC106728 AAI06729 D90277 BAA14321 D90278 BAA14322 DA674909 DC428993 E03348 E03349 L00692 AAA51969 L00693 AAA51970 NM_001277163 NP_001264092 NM_001815 NP_001806 NR_102333 |
Function | Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis. {ECO:0000269|PubMed:12864848, ECO:0000269|PubMed:14707113}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney. {ECO:0000269|PubMed:11708798}. |
Human CEACAM3 protein fragment - ab151918 from Abcam
|
||||||||||
CEACAM3-Antibody-C-term-Blocking-peptide - BP13855b from Abgent, a WuXi AppTec company
|
||||||||||
CEACAM3 protein (His tag) - 80R-4034 from Fitzgerald
|
||||||||||
CD66d / CEACAM3 (35-155, His-tag) - AR51719PU-N from Acris Antibodies
|
||||||||||
CD66d / CEACAM3 (35-155, His-tag) - AR51719PU-S from Acris Antibodies
|
||||||||||
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3, CEACAM3, Human, Recombinant - 19-C449 from ARP American Research Products
|
||||||||||
CEACAM3 fusion protein - ag17279 from Proteintech Group
|
||||||||||
CEACAM3 fusion protein - ag16632 from Proteintech Group
|
||||||||||
Recombinant Human CEACAM3 Protein - BP001695-C449 from Syd Labs
|
||||||||||
Recombinant Human CEACAM3 - CEACAM3-2698H from Creative Biomart
|
||||||||||
Recombinant Human CEACAM3, His tagged - CEACAM3-3942H from Creative Biomart
|
||||||||||
Recombinant Human carcinoembryonic antigen-related cell adhesion molecule 3, His-tagged - CEACAM3-676H from Creative Biomart
|
||||||||||
Recombinant Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) - RPC978Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) - RPC978Ra01 from Uscn Life Science Inc.
|
||||||||||
Human CEACAM3 / CD66d Protein (His Tag) - 11933-H08H-20 from Sino Biological
|
||||||||||
Recombinant Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) - RPC978Hu01 from Cloud-clone
|
||||||||||
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 3(CEAC - CSB-YP005163HU CSB-EP005163HU CSB-BP005163HU CSB-MP005163HU from Cusabio
|
||||||||||
CEACAM3, 35-155aa, Human, His tag, E.coli - ATGP2899 from ATGen
|
||||||||||
CD66d / CEACAM3 - TP317469 from Acris Antibodies
|
||||||||||
CD66d / CEACAM3 - TP720376 from Acris Antibodies
|
||||||||||
Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3), Recombinant Protein - MBS953848 from MyBioSource
|
||||||||||
CEACAM3, Recombinant Protein - MBS206035 from MyBioSource
|
||||||||||
Recombinant Human CEACAM3 / CD66d Protein (His tag) - PKSH030967 from Elabscience
|
||||||||||
CD66c/d Blocking Peptide - CBP7304 from Cohesion Biosciences
|
||||||||||
CEACAM-3/CD66d Recombinant Protein - NBP2-51908 from Novus Biologicals
|