IL18RAP

Gene Symbol	IL18RAP
Entrez Gene	8807
Alt Symbol	ACPL, CD218b, CDw218b, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RB
Species	Human
Gene Type	protein-coding
Description	interleukin 18 receptor accessory protein
Other Description	CD218 antigen-like family member B|IL-18 receptor accessory protein|IL-18 receptor beta|cluster of differentiation w218b|interleukin-1 receptor 7|interleukin-18 receptor accessory protein|interleukin-18 receptor beta
Swissprots	B2RPJ3 Q53TT4 O95256 Q3KPE7 Q53TU5 Q3KPE8
Accessions	AAY15049 AAY15080 CCF77059 EAX01791 O95256 AF077346 AAC72196 AK300026 BAG61837 BC069630 AAH69630 BC106764 AAI06765 BC106765 AAI06766 BC137474 AAI37475 BC137475 AAI37476 DN996214 DQ116957 AAZ52551 XM_011512087 XP_011510389 XM_011512088 XP_011510390 XM_011512089 XP_011510391 XR_923052 NM_003853 NP_003844
Function	Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK. {ECO:0000250, ECO:0000269|PubMed:9792649}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells. {ECO:0000269|PubMed:10925275, ECO:0000269|PubMed:11046021, ECO:0000269|PubMed:9792649}.
Top Pathways	Cytokine-cytokine receptor interaction, Inflammatory bowel disease (IBD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-IL18RAP-cDNA-Clone - DC09409 from Abgent, a WuXi AppTec company Prices $808.65 Sizes 10 µg Species Human Accession BC106765

Human IL-18 R beta/IL-1 R7 (NP_003844) VersaClone cDNA - RDC1118 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

IL18RAP - MBS1277130 from MyBioSource Species Human Accession BC106765

Human IL18RAP cDNA clone(NM_003853.2) - CDFH009160 from Creative Biomart Species Human Accession NM_003853.2

Human IL18RAP ORF clone(NM_003853.2) - CDCL184796 from Creative Biomart Species Human Accession NM_003853.2

Human IL18RAP ORF Clone(NM_003853.2) - CDCR286623 from Creative Biomart Species Human Accession NM_003853.2

Human IL18RAP ORF Clone(NM_003853.2) - CDCR286624 from Creative Biomart Species Human Accession NM_003853.2

Human IL18RAP ORF Clone(NM_003853.2) - CDCR286625 from Creative Biomart Species Human Accession NM_003853.2

Human IL18RAP ORF Clone(NM_003853.2) - CDCL167085 from Creative Biomart Species Human Accession NM_003853.2

Human IL18RAP Gene ORF cDNA clone in cloning vector - HG10176-M from Sino Biological Species Human

Human IL18RAP Gene ORF cDNA clone expression plasmid, C-His tag - HG10176-CH from Sino Biological Species Human

Human IL18RAP Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10176-NF from Sino Biological Species Human

Human IL18RAP Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10176-CF from Sino Biological Species Human

Human IL18RAP Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10176-NM from Sino Biological Species Human

Human IL18RAP Gene ORF cDNA clone expression plasmid, N-HA tag - HG10176-NY from Sino Biological Species Human

Human IL18RAP Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10176-ACG from Sino Biological Species Human

Human IL18RAP Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10176-CM from Sino Biological Species Human

Human IL18RAP / IL1R7 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10176-M-N from Sino Biological Species Human Accession NM_003853.2

Human IL18RAP Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10176-ACR from Sino Biological Species Human

Human IL18RAP Gene ORF cDNA clone expression plasmid, N-His tag - HG10176-NH from Sino Biological Species Human

Human IL18RAP / IL1R7 Gene cDNA Clone (full-length ORF Clone) expression ready, FLAG-tagged - HG10176-M-F from Sino Biological Species Human Accession NM_003853.2

Human IL18RAP Gene ORF cDNA clone expression plasmid - HG10176-UT from Sino Biological Species Human

Human IL18RAP Gene ORF cDNA clone expression plasmid, C-HA tag - HG10176-CY from Sino Biological Species Human

Human IL18RAP ORF clone(NM_003853.2) - CDCL184796 from Creative biogene Species Human

Human IL18RAP ORF Clone (BC106765) - CDCS411507 from Creative biogene Species Human Accession O95256

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