| Gene Symbol |
PHF11
|
| Entrez Gene |
51131
|
| Alt Symbol |
APY, BCAP, IGEL, IGER, IGHER, NY-REN-34, NYREN34
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
PHD finger protein 11
|
| Other Description |
BRCA1 C-terminus-associated protein|IgE responsiveness (atopic)|NY-REN-34 antigen|renal carcinoma antigen NY-REN-34
|
| Swissprots |
Q5W0A6 Q9Y5A2 Q5W0A4 Q9UIL8
|
| Accessions |
EAX08827 EAX08828 Q9UIL8 AB011031 BAA32101 AF155105 AAD42871 AK026228 AK225986 AK293242 BAG56776 AK300410 BAG62140 BC017212 AAH17212 BE621153 DA652444 DB050568 DQ891958 ABM82884 DQ895148 ABM86074 XM_005266417 XP_005266474 XM_006719828 XP_006719891 XM_006719829 XP_006719892 XM_006719830 XP_006719893 XM_011535102 XP_011533404 XR_245387 XR_941596 XR_941597 NM_016119 NM_001040443 NP_001035533 NM_001040444 NP_001035534
|
| Function |
Positive regulator of Th1-type cytokine gene expression. {ECO:0000269|PubMed:18405956}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:18405956}.
|
| Tissue Specificity |
Highly expressed in T and B-cells, as well as natural killer and mature dendritic cells. Expressed at higher levels in Th1 as compared to Th2 cells. Expressed at low levels in all normal tissues tested, including lung, testis, small intestine, breast, liver and placenta. {ECO:0000269|PubMed:18405956}.
|
![Western Blot: PHF11 Overexpression Lysate (Adult Normal) [NBL1-14353] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PHF11.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1301_PHF11%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14353-img0002.jpg)