UFM1

Gene Symbol UFM1
Entrez Gene 51569
Alt Symbol BM-002, C13orf20
Species Human
Gene Type protein-coding
Description ubiquitin-fold modifier 1
Other Description -
Swissprots P61960 Q5VXS0 Q6IAG6
Accessions EAX08605 P61960 AB154404 BAD15373 AF208844 AAF64258 AF369953 AK095490 AK307111 AK309914 AL515797 BC005193 AAH05193 BG533062 BG540094 BG717690 BI458294 BI761948 BM683574 BP277186 BQ002588 BU069122 BU589105 CB070175 CN362375 CR457189 CAG33470 DA448931 DA483023 JF432449 ADZ15666 Z70222 CAA94181 NM_001286703 NP_001273632 NM_001286704 NP_001273633 NM_001286705 NP_001273634 NM_001286706 NP_001273635 NM_016617 NP_057701 NR_104584 NR_104585
Function Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes. TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (By similarity). {ECO:0000250|UniProtKB:P61961, ECO:0000269|PubMed:15071506, ECO:0000269|PubMed:20018847, ECO:0000269|PubMed:25219498}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15071506}. Cytoplasm {ECO:0000269|PubMed:15071506}.

Human-UFM1-cDNA-Clone - DC01656 from Abgent, a WuXi AppTec company

Prices $114.75
Sizes 10 µg
Species Human
Accession BC005193

UFM1 - MBS1270312 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC005193

human UFM1 ORF clone - CDCH097916 from Creative Biomart

Species Human
Accession NM_016617

human UFM1 ORF clone - CDCH097917 from Creative Biomart

Species Human
Accession NM_016617

Human UFM1 ORF Clone(NM_016617.2) - CDCL180463 from Creative Biomart

Species Human
Accession NM_016617.2

Human UFM1 ORF Clone (BC005193) - CDCS414359 from Creative biogene

Species Human
Accession P61960
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