UFM1

Gene Symbol	UFM1
Entrez Gene	51569
Alt Symbol	BM-002, C13orf20
Species	Human
Gene Type	protein-coding
Description	ubiquitin-fold modifier 1
Other Description	-
Swissprots	P61960 Q5VXS0 Q6IAG6
Accessions	EAX08605 P61960 AB154404 BAD15373 AF208844 AAF64258 AF369953 AK095490 AK307111 AK309914 AL515797 BC005193 AAH05193 BG533062 BG540094 BG717690 BI458294 BI761948 BM683574 BP277186 BQ002588 BU069122 BU589105 CB070175 CN362375 CR457189 CAG33470 DA448931 DA483023 JF432449 ADZ15666 Z70222 CAA94181 NM_001286703 NP_001273632 NM_001286704 NP_001273633 NM_001286705 NP_001273634 NM_001286706 NP_001273635 NM_016617 NP_057701 NR_104584 NR_104585
Function	Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes. TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (By similarity). {ECO:0000250|UniProtKB:P61961, ECO:0000269|PubMed:15071506, ECO:0000269|PubMed:20018847, ECO:0000269|PubMed:25219498}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15071506}. Cytoplasm {ECO:0000269|PubMed:15071506}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human UFM1 (mutated S84 + C85) full length protein - ab190025 from Abcam Category Protein Prices $342.00 Sizes 250 µg Source E. coli Species Human

Active human UFM1 full length protein - ab190029 from Abcam Category Protein Prices $342.00 Sizes 500 µl Source E. coli Species Human

Human UFM1 full length protein - ab104461 from Abcam Category Protein Source E. coli Species Human

Human UFM1 full length protein - ab124867 from Abcam Category Protein Source E. coli Species Human

UFM1 Antibody Blocking Peptide - LS-E21730 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UFM1 Recombinant Protein - H00051569-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human UFM1 Protein - NBP1-51015 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Recombinant Human His6-UFM1, CF - UL-500-250 from R&D Systems Category Protein

Recombinant Human UFM1 Agarose, CF - UL-530-500 from R&D Systems Category Protein Source E. coli-derived,

Recombinant Human UFM1 Rhodamine, CF - UL-522-050 from R&D Systems Category Protein Source E. coli-derived,

Recombinant Human His6-Pro-UFM1, CF - UL-505-250 from R&D Systems Category Protein Source E. coli-derived, Contains an N-terminal 6-His tag

Recombinant Human UFM1 Fluorescein, CF - UL-521-050 from R&D Systems Category Protein Source E. coli-derived,

Human UFM1 protein - orb169522 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

UFM1 protein (His tag) - 80R-1698 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

Ubiquitin-fold modifier 1 (UFM1) (1-83, His-tag) - AR09880PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Ubiquitin-fold modifier 1 (UFM1) (1-83, His-tag) - AR09880PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Ubiquitin-fold modifier 1 (UFM1) - H00051569-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Ubiquitin-fold modifier 1 (UFM1) - H00051569-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Ubiquitin-Fold Modifier 1, Human Recombinant - 228-12881-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Ubiquitin-Fold Modifier 1 - 228-12881-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Ubiquitin-Fold Modifier 1 - 228-12881-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

UFM1, 1-83aa, Human, His tag, E.coli - 01-P0940 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

UFM1 fusion protein - Ag8667 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

UFM1 fusion protein - ag8686 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

UFM1 Human - PRPS-132 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

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