| Gene Symbol |
TNFRSF13C
|
| Entrez Gene |
115650
|
| Alt Symbol |
BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tumor necrosis factor receptor superfamily, member 13C
|
| Other Description |
B cell-activating factor receptor|B-cell-activating factor receptor|BAFF receptor|BLyS receptor 3|tumor necrosis factor receptor superfamily member 13C
|
| Swissprots |
Q96RJ3
|
| Accessions |
ABK41893 BAE16554 CAZ39524 CBF13296 CBH32711 CBH51798 CBI12201 CBI67648 CBX33268 CDG23825 EAW60473 Q96RJ3 AF373846 AAK91826 AX772914 CAE06271 AX800072 CAE51828 BC105123 AAI05124 BC111585 AAI11586 BC112030 AAI12031 NM_052945 NP_443177
|
| Function |
B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. {ECO:0000269|PubMed:11591325, ECO:0000269|PubMed:12387744}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Primary immunodeficiency, Intestinal immune network for IgA production, HTLV-I infection
|
![Western Blot: BAFF Receptor Overexpression Lysate (Adult Normal) [NBL1-17149] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for BAFF Receptor.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1046_BAFF%2520Receptor%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17149-img0002.jpg)