| Gene Symbol | CD80 |
|---|---|
| Entrez Gene | 100009377 |
| Alt Symbol | - |
| Species | Rabbit |
| Gene Type | protein-coding |
| Description | CD80 molecule |
| Other Description | T-lymphocyte activation antigen CD80|activation B7-1 antigen |
| Swissprots | P42070 |
| Accessions | P42070 D49843 BAA08643 XM_008266820 XP_008265042 XM_008266821 XP_008265043 XM_008266822 XP_008265044 NM_001082663 NP_001076132 |
| Function | Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Top Pathways | Toll-like receptor signaling pathway, Rheumatoid arthritis, Intestinal immune network for IgA production, Type I diabetes mellitus, Graft-versus-host disease |