TWF1

Gene Symbol TWF1
Entrez Gene 5756
Alt Symbol A6, PTK9
Species Human
Gene Type protein-coding
Description twinfilin actin-binding protein 1
Other Description A6 protein tyrosine kinase|PTK9 protein tyrosine kinase 9|protein A6|protein tyrosine kinase 9|twinfilin, actin-binding protein, homolog 1|twinfilin-1
Swissprots Q86XL6 B3KXS6 Q8TCD3 Q59G07 Q6FHL6 Q6FHJ1 Q6NUK9 B4DLX9 Q12792 A8K5A8 Q5U0B1
Accessions EAW57868 EAW57869 EAW57870 Q12792 AB209302 BAD92539 AK127868 BAG54588 AK291223 BAF83912 AK297206 BAG59691 BC022344 AAH22344 BC022491 BC043148 AAH43148 BC068548 AAH68548 BT019691 AAV38497 CR541736 CAG46536 CR541761 CAG46561 EU832120 ACE87470 EU832214 ACE86784 U02680 AAC50062 NM_001242397 NP_001229326 NM_002822 NP_002813 NR_073472 NR_073473 NM_198974
Function Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Diffuse cytoplasmic localization with perinuclear and G-actin-rich cortical actin structures sublocalization. Also found at membrane ruffles and cell-cell contacts (By similarity). {ECO:0000250}.
Tissue Specificity Expressed at high levels in the colon, testis, ovary, prostate and lung. Expressed at lower levels in the brain, bladder and heart. Not detected in liver. {ECO:0000269|PubMed:7507208}.

Twinfilin-1 (D7C6J) Rabbit mAb - 14138 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D7C6J
Western blot analysis of extracts from various cell lines using Twinfilin-1 (D7C6J) Rabbit mAb.

Twinfilin-1 Antibody - 8461 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Twinfilin-1 Antibody.

Twinfilin-1 (C-19) - sc-51241 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Twinfilin-1 (C-19): sc-51241. Western blot analysis of Twinfilin-1 expression in non-transfected: sc-117752 (A) and mouse Twinfilin-1 transfected: sc-124373 (B) 293T whole cell lysates.

Twinfilin-1 (G-16) - sc-51242 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Twinfilin-1 (H-62) - sc-292576 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Twinfilin-1 (H-62): sc-292576. Western blot analysis of human recombinant Twinfilin-1 fusion protein.

Twinfilin-1 (N-13) - sc-51243 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

p-Twinfilin-1 (Tyr 327) - sc-130609 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-PTK9 antibody - ab127181 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-PTK9 antibody (ab127181) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-PTK9 antibody - ab88698 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-PTK9 antibody (ab88698) at 1 µg/ml + human colon tissue lysate at 50 µg

Anti-PTK9 antibody - ab55634 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PTK9 antibody [7C11] - ab135236 from Abcam

Host Mouse
Clonality Monoclonal
Clone 7C11
Anti-PTK9 antibody [7C11] (ab135236) at 1/500 dilution + Human PTK9 recombinant protein

Anti-TWF1 / PTK9 Antibody (aa1-252) - LS-C296894 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TWF1 / PTK9 Antibody (aa1-252, Biotin) - LS-C297394 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TWF1 / PTK9 Antibody (aa1-252, FITC) - LS-C304996 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TWF1 / PTK9 Antibody (aa191-240) - LS-C145235 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TWF1 / PTK9 antibody LS-C145235 Western blot of Rat Brain lysate. Antibody concentration 1 ug/ml.

Anti-TWF1 / PTK9 Antibody (N-Terminus) - LS-C111930 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TWF1 / PTK9 antibody LS-C111930 Western blot of Fetal Brain lysate.

Anti-TWF1 / PTK9 Antibody - LS-C155501 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using PTK9 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with alpha-tubulin antibody (Red) at 1:2000.

Anti-TWF1 / PTK9 Antibody (clone 1E2) - LS-C104900 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E2
PTK9 monoclonal antibody (M02), clone 1E2. Western blot of PTK9 expression in PC-12.

Anti-TWF1 / PTK9 Antibody (clone 7C11) - LS-C169121 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7C11
IHC of paraffin-embedded ovarian cancer tissues using TWF1 mouse monoclonal antibody with DAB staining.

PTK9 Antibody (7C11) - NBP2-37456 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7C11
Western Blot: PTK9 Antibody (7C11) [NBP2-37456] - Western blot analysis using TWF1 mAb against HEK293 (1) and TWF1 (AA: 335-384)-hIgGFc transfected HEK293 (2) cell lysate.

PTK9 Antibody (1E2.) - H00005756-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E2.
Western Blot: PTK9 Antibody (1E2) [H00005756-M02] - PTK9 monoclonal antibody (M02), clone 1E2 Analysis of PTK9 expression in HeLa.

PTK9 Antibody - NBP1-90297 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PTK9 Antibody [NBP1-90297] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

PTK9 Antibody - NBP1-33132 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PTK9 Antibody (5C4) - H00005756-M06 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5C4

PTK9 Antibody (1D12) - H00005756-M05 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D12
Western Blot: PTK9 Antibody (1D12) [H00005756-M05] - Western blot analysis of PTK9 over-expressed 293 cell line, cotransfected with PTK9 Validated Chimera RNAi or non-transfected control. Blot probed with H00005756-M05. GAPDH (36.1 kDa) used as loading control.
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