TWF1

Gene Symbol	TWF1
Entrez Gene	5756
Alt Symbol	A6, PTK9
Species	Human
Gene Type	protein-coding
Description	twinfilin actin-binding protein 1
Other Description	A6 protein tyrosine kinase|PTK9 protein tyrosine kinase 9|protein A6|protein tyrosine kinase 9|twinfilin, actin-binding protein, homolog 1|twinfilin-1
Swissprots	Q86XL6 B3KXS6 Q8TCD3 Q59G07 Q6FHL6 Q6FHJ1 Q6NUK9 B4DLX9 Q12792 A8K5A8 Q5U0B1
Accessions	EAW57868 EAW57869 EAW57870 Q12792 AB209302 BAD92539 AK127868 BAG54588 AK291223 BAF83912 AK297206 BAG59691 BC022344 AAH22344 BC022491 BC043148 AAH43148 BC068548 AAH68548 BT019691 AAV38497 CR541736 CAG46536 CR541761 CAG46561 EU832120 ACE87470 EU832214 ACE86784 U02680 AAC50062 NM_001242397 NP_001229326 NM_002822 NP_002813 NR_073472 NR_073473 NM_198974
Function	Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Diffuse cytoplasmic localization with perinuclear and G-actin-rich cortical actin structures sublocalization. Also found at membrane ruffles and cell-cell contacts (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed at high levels in the colon, testis, ovary, prostate and lung. Expressed at lower levels in the brain, bladder and heart. Not detected in liver. {ECO:0000269|PubMed:7507208}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PTK9 full length protein - ab131676 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human PTK9 full length protein - ab132587 from Abcam Category Protein Source Wheat germ Species Human

Human PTK9 protein fragment - ab116148 from Abcam Category Protein Source E. coli Species Human

TWF1 / PTK9 Antibody Blocking Peptide - LS-E20516 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TWF1 / PTK9 Antibody Blocking Peptide - LS-E20517 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PTK9 Partial Recombinant Protein - H00005756-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PTK9 Recombinant Protein - H00005756-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human PTK9 Protein - NBP1-78821 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E. coli Species Human

Human TWF1 His GST tag protein - orb84100 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Human TWF1 protein - orb169490 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Human TWF1 protein - orb84101 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Twf1 Blocking Peptide - 33R-2514 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TWF1 Blocking Peptide - 33R-6441 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TWF1 protein (His tag) - 80R-2064 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

Human Twinfilin 1 Protein - abx069579 from Abbexa Category Protein Source E.coli Species Human

Twinfilin-1 (TWF1) (1-252, His-tag) - AR50147PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

Twinfilin-1 (TWF1) (1-252, His-tag) - AR50147PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

Twinfilin-1 (TWF1) - H00005756-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Twinfilin-1 (TWF1) - H00005756-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Twinfilin-1 (TWF1) - H00005756-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Twinfilin-1 (TWF1) - H00005756-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Twinfilin-1, Human Recombinant - 228-12823-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Twinfilin-1 - 228-12823-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source E.coli. Species Human

Recombinant Human Twinfilin-1 - 228-12823-3 from RayBiotech Category Protein Source E.coli. Species Human

TWF1, 1-252aa, Human, His tag, E.coli - 01-P1322 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

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