CORO1A

Gene Symbol	CORO1A
Entrez Gene	11151
Alt Symbol	CLABP, CLIPINA, HCORO1, IMD8, TACO, p57
Species	Human
Gene Type	protein-coding
Description	coronin, actin binding protein, 1A
Other Description	clipin-A\|coronin-1\|coronin-1A\|coronin-like protein A\|coronin-like protein p57\|tryptophan aspartate-containing coat protein
Swissprots	B2RBL1 P31146 Q2YD73
Accessions	EAW79906 EAW79907 EAW79908 EAW79909 EAW79910 P31146 AB209221 BAD92458 AF495470 AAM18516 AK096332 AK097964 AK123401 BAC85606 AK296207 BAG58933 AK314714 BAG37258 BC110374 AAI10375 BC126385 AAI26386 BC126387 AAI26388 CD623635 D44497 BAA07940 DA256300 DC408372 EU446773 ABZ92302 GQ214031 HQ258407 ADR83161 U34690 AAA77058 X89109 CAA61482 XM_011545714 XP_011544016 NM_001193333 NP_001180262 NM_007074 NP_009005
Function	May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes. {ECO:0000269\|PubMed:10338208}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}. Note=In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed in brain, thymus, spleen, bone marrow and lymph node. Low in lung and gut.
Top Pathways	Phagosome, Tuberculosis

Coronin 1A (14.1) - sc-100925 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

Coronin 1A (14.1): sc-100925. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung tissue showing nuclear and cytoplasmic localization.

Coronin 1A (E-21) - sc-133476 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

Coronin 1A (E-21): sc-133476. Western blot analysis of Coronin 1A expression in Jurkat whole cell lysate.

Coronin 1A (H-300) - sc-366201 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Coronin 1A (H-300): sc-366201. Western blot analysis of Coronin 1A expression in Jurkat (A), HL-60 (B) and A549 (C) whole cell lysates and mouse spleen tissue extract (D).

Coronin 1A (K-16) - sc-49423 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Coronin 1A (V-14) - sc-49425 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-Coronin 1a antibody - ab56820 from Abcam

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Coronin 1a antibody (ab56820) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lung.

Anti-Coronin 1a antibody - ab14787 from Abcam

Prices	$385.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-Coronin 1a antibody (ab14787) at 0.3 µg/ml + Cell lysates prepared from Jurkat cells at 35 µg

Anti-Coronin 1a antibody - ab123574 from Abcam

Prices	$376.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

ab123574, at 1/10000, staining Coronin 1a (green) in a mixed neuron/glial culture from newborn rat brain, by immunocytochemistry. Red staining is from an anti-Vimentin antibody, while blue is a nuclear DNA counter stain.

Anti-Coronin 1a antibody - ab115673 from Abcam

Prices	$384.00
Sizes	50 µg
Host	Goat
Clonality	Polyclonal

Anti-Coronin 1a antibody (ab115673) at 0.3 µg/ml + Jurkat lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-Coronin 1a antibody - ab53395 from Abcam

Prices	$378.00
Sizes	100 µl
Host	Chicken
Clonality	Polyclonal

Ab53395 at 1/1000 dilution staining cultured adult mouse brain cells.

Anti-Coronin 1a antibody - ab72212 from Abcam

Prices	$384.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human stomach carcinoma tissue labelling Coronin 1a with ab72212 at 1/1000 (0.2µg/ml). Detection: DAB.

Anti-Coronin 1a antibody - ab75711 from Abcam

Prices	$370.00
Sizes	500 µl
Host	Chicken
Clonality	Polyclonal

Anti-Coronin 1a antibody - ab84504 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human Coronin 1a by Immunohistochemistry on formalin fixed paraffin embedded section of Human stomach adenocarcinoma using 1/250 ab84504. Detection: DAB staining

Anti-Coronin 1a antibody - ab66374 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Coronin 1a antibody (ab66374) at 1.25 µg/ml + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Coronin 1a antibody [1A5] - ab119094 from Abcam

Prices	$384.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1A5

All lanes : Anti-Coronin 1a antibody [1A5] (ab119094) at 1/500 dilutionLane 1 : Lysate from HEK293T cells transfected with vector alone.Lane 2 : Lysate from HEK293T cells transfected with a vector expressing full length Coronin 1a.Lysates/proteins at 5 µg per lane.developed using the ECL technique

Anti-CORO1A / p57 Antibody - LS-C79768 from LifeSpan Bioscience

Host	Chicken
Clonality	Polyclonal

Anti-CORO1A / p57 Antibody - LS-C79774 from LifeSpan Bioscience

Host	Chicken
Clonality	Polyclonal

Anti-CORO1A / p57 Antibody (aa181-230) - LS-C30171 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CORO1A / p57 Antibody (C-Terminus) - LS-C31090 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CORO1A / p57 Antibody (N-Terminus) - LS-C31093 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CORO1A / p57 Antibody (C-Terminus) - LS-C31095 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CORO1A / p57 Antibody - LS-C123324 from LifeSpan Bioscience

Host	Chicken
Clonality	Polyclonal

Anti-CORO1A / p57 Antibody - LS-C149096 from LifeSpan Bioscience

Host	Chicken
Clonality	Polyclonal

Anti-CORO1A / p57 Antibody (clone KP10) - LS-C202894 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal
Clone	KP10

Anti-CORO1A / p57 Antibody (Ser306) - LS-C176548 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Western blot of p57 (S306) pAb in extracts from K562 cells.

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