| Gene Symbol | Chtop |
|---|---|
| Entrez Gene | 66511 |
| Alt Symbol | 2500003M10Rik, Fop, Srag |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | chromatin target of PRMT1 |
| Other Description | Friend of PRMT1 protein|chromatin target of PRMT1 protein|small arginine- and glycine-rich protein|small protein rich in arginine and glycine |
| Swissprots | Q9DB03 Q5XJG9 Q0VBG3 Q9CY57 Q9DC54 Q3UF43 Q8C5N4 Q3V105 Q9D7T3 Q3U7V6 Q9JJ95 |
| Accessions | EDL15128 EDL15129 EDL15130 EDL15131 EDL15132 EDL15133 EDL15134 EDL15135 Q9CY57 AB041654 BAA95102 AK004558 BAB23371 AK005377 BAB23984 AK008885 BAB25951 AK010866 BAB27232 AK047914 BAC33189 AK077960 BAC37084 AK132769 BAE21348 AK135914 AK149010 BAE28718 AK152492 BAE31263 AK189597 AK190161 AK204756 AK208473 AK211997 BC004582 AAH04582 BC051939 BC066837 BC083333 AAH83333 BC108396 AAI08397 BC120651 AAI20652 BC144775 AAI44776 BE852996 BQ746440 CX234428 XR_375563 XR_867226 NM_001293776 NP_001280705 NM_001293777 NP_001280706 NM_001293778 NP_001280707 NM_001293779 NP_001280708 NM_001293780 NP_001280709 NM_001293781 NP_001280710 NM_001293782 NP_001280711 NM_023215 NP_075704 |
| Function | Plays an important role in the ligand-dependent activation of estrogen receptor target genes (By similarity). May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. {ECO:0000250, ECO:0000269|PubMed:20688955, ECO:0000269|PubMed:22872859}. |
| Subcellular Location | Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Mostly associated with facultative heterochromatin. |
| Tissue Specificity | Broadly expressed with highest levels found in thymus, spleen, and lymph nodes. Expressed in an erythroid progenitor cell line derived from fetal liver. {ECO:0000269|PubMed:19254951, ECO:0000269|PubMed:20688955}. |