ATL1

Gene Symbol	ATL1
Entrez Gene	51062
Alt Symbol	AD-FSP, FSP1, GBP3, HSN1D, SPG3, SPG3A, atlastin1
Species	Human
Gene Type	protein-coding
Description	atlastin GTPase 1
Other Description	GBP-3|GTP-binding protein 3|atlastin-1|brain-specific GTP-binding protein|guanine nucleotide-binding protein 3|guanylate-binding protein 3|hGBP3|spastic paraplegia 3 protein A
Swissprots	A6NND5 O95890 Q8WXF7 Q69YH7 Q96FK0 A8K2C0 G5E9T1
Accessions	CAH25961 EAW65705 EAW65706 EAW65707 EAW65708 EAW65709 Q8WXF7 AF131801 AAD20047 AF444143 AAL37898 AK223436 BAD97156 AK290185 BAF82874 AK312518 AL833591 CAH10392 AW674605 AY032844 AAK51160 BC010708 AAH10708 BG704589 BI601372 CR457153 CAG33434 DA088230 DA397302 R61338 NM_001127713 NP_001121185 NM_015915 NP_056999 NM_181598 NP_853629
Function	GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development. {ECO:0000269|PubMed:14506257, ECO:0000269|PubMed:17321752, ECO:0000269|PubMed:18270207, ECO:0000269|PubMed:19665976, ECO:0000269|PubMed:21220294, ECO:0000269|PubMed:23334294}.
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, axon {ECO:0000250}.
Tissue Specificity	Expressed predominantly in the adult and fetal central nervous system. Measurable expression in all tissues examined, although expression in adult brain is at least 50-fold higher than in other tissues. Detected predominantly in pyramidal neurons in the cerebral cortex and the hippocampus of the brain. Expressed in upper and lower motor neurons (at protein level). {ECO:0000269|PubMed:14506257, ECO:0000269|PubMed:17321752, ECO:0000269|PubMed:18270207}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SPG3A gene - orb91102 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human-ATL1-cDNA-Clone - DC02985 from Abgent, a WuXi AppTec company Prices $753.30 Sizes 10 µg Species Human Accession BC010708

ATL1 - MBS1270145 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC010708

Human SPG3A transcript variant 1 Gene cDNA clone plasmid - HG10523-M from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid - HG10523-UT from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10523-NH from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10523-ACG from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10523-M-F from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10523-NF from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10523-NM from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10523-CY from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10523-CF from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10523-NY from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10523-CM from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10523-ANG from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10523-CH from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10523-ACR from Sino Biological Species Human

Human SPG3A/ATL1 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10523-ANR from Sino Biological Species Human

Human SPG3A ORF clone(NM_015915.4) - CDCL186276 from Creative biogene Species Human

Human ATL1 ORF Clone(NM_001127713.1) - CDCR348894 from Creative biogene Species Human

Human ATL1 ORF clone (NM_181598.3) - CDCR031480 from Creative biogene Species Human

Human ATL1 ORF Clone (BC010708) - CDCS407824 from Creative biogene Species Human Accession Q8WXF7

Human ATL1 cDNA Clone(NM_001127713.1) - CDFH001369 from Creative biogene Species Human

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