ATL1

Gene Symbol ATL1
Entrez Gene 51062
Alt Symbol AD-FSP, FSP1, GBP3, HSN1D, SPG3, SPG3A, atlastin1
Species Human
Gene Type protein-coding
Description atlastin GTPase 1
Other Description GBP-3|GTP-binding protein 3|atlastin-1|brain-specific GTP-binding protein|guanine nucleotide-binding protein 3|guanylate-binding protein 3|hGBP3|spastic paraplegia 3 protein A
Swissprots A6NND5 O95890 Q8WXF7 Q69YH7 Q96FK0 A8K2C0 G5E9T1
Accessions CAH25961 EAW65705 EAW65706 EAW65707 EAW65708 EAW65709 Q8WXF7 AF131801 AAD20047 AF444143 AAL37898 AK223436 BAD97156 AK290185 BAF82874 AK312518 AL833591 CAH10392 AW674605 AY032844 AAK51160 BC010708 AAH10708 BG704589 BI601372 CR457153 CAG33434 DA088230 DA397302 R61338 NM_001127713 NP_001121185 NM_015915 NP_056999 NM_181598 NP_853629
Function GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development. {ECO:0000269|PubMed:14506257, ECO:0000269|PubMed:17321752, ECO:0000269|PubMed:18270207, ECO:0000269|PubMed:19665976, ECO:0000269|PubMed:21220294, ECO:0000269|PubMed:23334294}.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, axon {ECO:0000250}.
Tissue Specificity Expressed predominantly in the adult and fetal central nervous system. Measurable expression in all tissues examined, although expression in adult brain is at least 50-fold higher than in other tissues. Detected predominantly in pyramidal neurons in the cerebral cortex and the hippocampus of the brain. Expressed in upper and lower motor neurons (at protein level). {ECO:0000269|PubMed:14506257, ECO:0000269|PubMed:17321752, ECO:0000269|PubMed:18270207}.

Human SPG3A protein fragment - ab153326 from Abcam

Category Protein
Source Wheat germ
Species Human
ab153326 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ATL1-Antibody-C-term-Blocking-Peptide - BP16799b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human SPG3A GST tag protein - orb83719 from Biorbyt

Category Protein
Prices $323.00, $646.00
Sizes 20 μg, 100 μg
Source Insect
Species Human
SDS-PAGE analysis of human SPG3A GST tag protein

Atlastin-1 / SPG3A - H00051062-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Atlastin-1 / SPG3A - H00051062-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

ATL1 fusion protein - Ag2797 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PKG
Species Human

Recombinant Human ATL1, GST tagged - ATL1-3333H from Creative Biomart

Category Protein
Source Baculovirus-Insect Cells
Species Human

Recombinant Human ATL1, GST-tagged - ATL1-9984H from Creative Biomart

Category Protein
Source E.coli
Species Human

Atlastin-1 / SPG3A (transcript variant 1) - TP302310 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
Atlastin-1 / SPG3A
Search more