| Gene Symbol |
EEF1E1
|
| Entrez Gene |
9521
|
| Alt Symbol |
AIMP3, P18
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
eukaryotic translation elongation factor 1 epsilon 1
|
| Other Description |
ARS-interacting multifunctional protein 3|aminoacyl tRNA synthetase complex-interacting multifunctional protein 3|eukaryotic translation elongation factor 1 epsilon-1|multisynthase complex auxiliary component p18|p18 component of aminoacyl-tRNA synthetase complex
|
| Swissprots |
O43324 Q5THS2 C9JLK5
|
| Accessions |
EAW55227 EAW55231 O43324 AB011079 BAA24926 AF054186 AAC39916 AI374688 AI394376 AV714140 BC005291 AAH05291 BG183264 BP235196 BT007306 AAP35970 CK002875 DQ893502 ABM84428 EU176776 ABW03577 NM_001135650 NP_001129122 NM_004280 NP_004271
|
| Function |
Positive modulator of ATM response to DNA damage.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15680327}. Nucleus {ECO:0000269|PubMed:15680327}. Note=Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes (S phase) and following DNA damage.
|
| Tissue Specificity |
Down-regulated in various cancer tissues. {ECO:0000269|PubMed:15680327}.
|
![Western Blot: EEF1E1 Overexpression Lysate (Adult Normal) [NBL1-10126] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for EEF1E1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1417_EEF1E1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10126-img0002.jpg)