| Gene Symbol |
LTBP4
|
| Entrez Gene |
8425
|
| Alt Symbol |
ARCL1C, LTBP-4, LTBP4L, LTBP4S
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
latent transforming growth factor beta binding protein 4
|
| Other Description |
latent transforming growth factor-beta binding protein 4L|latent-transforming growth factor beta-binding protein 4
|
| Swissprots |
O75412 Q8N2S1 O00508 O75413
|
| Accessions |
CBX47603 CBX47604 CBX47605 EAW56982 EAW56983 EAW56984 EAW56985 Q8N2S1 AF051344 AAC39879 AF051345 AAC39880 AF054501 AAC39881 AF054502 AAC39882 AK074499 BAC11024 AK128191 BAG54648 AK303613 BAH13998 AK304612 BAH14224 AK309484 BQ001109 Y13622 CAA73944 XM_011527376 XP_011525678 XM_011527377 XP_011525679 XM_011527378 XP_011525680 XM_011527379 XP_011525681 XM_011527380 XP_011525682 XM_011527381 XP_011525683 XM_011527382 XP_011525684 XM_011527383 XP_011525685 XM_011527384 XP_011525686 XM_011527385 XP_011525687 XM_011527386 XP_011525688 XM_011527387 XP_011525689 NM_001042544 NP_001036009 NM_001042545 NP_001036010 NM_003573 NP_003564
|
| Function |
May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM) (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:16157329, ECO:0000269|PubMed:9660815}.
|
| Tissue Specificity |
Highly expressed in heart, skeletal muscle, pancreas, uterus, and small intestine. Weakly expressed in placenta and lung. {ECO:0000269|PubMed:9271198, ECO:0000269|PubMed:9660815}.
|