Gene Symbol | CNNM4 |
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Entrez Gene | 26504 |
Alt Symbol | ACDP4 |
Species | Human |
Gene Type | protein-coding |
Description | cyclin and CBS domain divalent metal cation transport mediator 4 |
Other Description | ancient conserved domain protein 4|ancient conserved domain-containing protein 4|cyclin M4|cyclin-M4|metal transporter CNNM4 |
Swissprots | Q6P4Q7 B7Z1U0 Q9H9G3 Q53RE5 C7SQM5 C7SQM4 Q9NRN1 C7SQM3 Q9HCI0 |
Accessions | AAY14963 ACV32670 ACV32671 ACV32672 EAW71340 Q6P4Q7 AB046812 BAB13418 AF202777 AAF86370 AK022833 BAB14266 AK095065 AK293915 BAH11626 AL833905 CAD38761 BC063295 AAH63295 XM_005263914 XP_005263971 XM_005263915 XP_005263972 XM_011510955 XP_011509257 XM_011510956 XP_011509258 NM_020184 NP_064569 |
Function | Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function. {ECO:0000250, ECO:0000269|PubMed:19200525, ECO:0000269|PubMed:19200527}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:22399287}; Multi-pass membrane protein {ECO:0000269|PubMed:22399287}. |
Tissue Specificity | Widely expressed. Highly expressed in heart. {ECO:0000269|PubMed:12657465}. |
cyclin M4 CRISPR/Cas9 KO Plasmid (h) - sc-408217 from Santa Cruz Biotechnology
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cyclin M4 HDR Plasmid (h) - sc-408217-HDR from Santa Cruz Biotechnology
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cyclin M4 Double Nickase Plasmid (h) - sc-408217-NIC from Santa Cruz Biotechnology
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cyclin M4 Double Nickase Plasmid (h2) - sc-408217-NIC-2 from Santa Cruz Biotechnology
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cyclin M4 CRISPR Activation Plasmid (h) - sc-408217-ACT from Santa Cruz Biotechnology
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cyclin M4 CRISPR Activation Plasmid (h2) - sc-408217-ACT-2 from Santa Cruz Biotechnology
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cyclin M4 Lentiviral Activation Particles (h) - sc-408217-LAC from Santa Cruz Biotechnology
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cyclin M4 Lentiviral Activation Particles (h2) - sc-408217-LAC-2 from Santa Cruz Biotechnology
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cyclin M4 siRNA (h) - sc-77065 from Santa Cruz Biotechnology
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cyclin M4 shRNA Plasmid (h) - sc-77065-SH from Santa Cruz Biotechnology
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cyclin M4 shRNA (h) Lentiviral Particles - sc-77065-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU006611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6316 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6316 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11360 from Sigma-Aldrich
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CNNM4 siRNA (Human) - CRH8835 from Cohesion Biosciences
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CNNM4 - MBS8228795 from MyBioSource
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shRNA set against Human CNNM4 (NM_020184.3) - SHH266377 from Creative biogene
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shRNA set against Human CNNM4(NM_020184.3) - SHG187531 from Creative biogene
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Human CNNM4 siRNA - orb269337 from Biorbyt
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CNNM4 shRNA Plasmid (Human) - CHH8835 from Cohesion Biosciences
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CNNM4 miRNA 3'UTR clone - MiUTR1H-02277 from Creative biogene
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