| Gene Symbol | IL2 |
|---|---|
| Entrez Gene | 3558 |
| Alt Symbol | IL-2, TCGF, lymphokine |
| Species | Human |
| Gene Type | protein-coding |
| Description | interleukin 2 |
| Other Description | T cell growth factor|aldesleukin|interleukin-2|involved in regulation of T-cell clonal expansion |
| Swissprots | P01585 P60568 |
| Accessions | AAA59139 AAA59140 AAA59141 AAA98792 AAB86861 AAD48509 AAK26665 CAA07317 CAA25292 CAA47701 CAH18032 CAT16485 CBH19848 CBX47490 EAX05227 P60568 A14844 CAA01199 AB451325 BAG70139 AB451454 BAG70268 AF228636 AAG53575 AF532913 AAM97916 AY283686 AAP35033 AY523040 AAS17753 BC066254 AAH66254 BC066255 AAH66255 BC066256 AAH66256 BC066257 AAH66257 BC070338 AAH70338 DQ231169 ABB20900 DQ861285 ABI20697 HQ447521 ADQ32007 S77834 AAD14263 S77835 AAD14264 S82692 AAB46883 U25676 AAA70092 V00564 CAA23827 X01586 CAA25742 NM_000586 NP_000577 |
| Function | Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells. |
| Subcellular Location | Secreted. |
| Top Pathways | Inflammatory bowel disease (IBD), Measles, PI3K-Akt signaling pathway, HTLV-I infection, Cytokine-cytokine receptor interaction |