| Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). Nicotinic acetylcholine receptor in the MC pharyngeal motor neuron involved in pharyngeal pumping. Has a role in the determination of life span possibly via calorific restriction which affects growth rate, although this is independent of metabolic activity. {ECO:0000250|UniProtKB:P22770, ECO:0000269|PubMed:15020415, ECO:0000269|PubMed:15141086, ECO:0000269|PubMed:8462849, ECO:0000269|PubMed:8601480, ECO:0000269|PubMed:9789046}.
|