ERCC3

Gene Symbol	ERCC3
Entrez Gene	2071
Alt Symbol	BTF2, GTF2H, RAD25, TFIIH, XPB
Species	Human
Gene Type	protein-coding
Description	excision repair cross-complementation group 3
Other Description	BTF2 p89|DNA excision repair protein ERCC-3|DNA repair helicase|DNA repair protein complementing XP-B cells|TFIIH 89 kDa subunit|TFIIH basal transcription factor complex 89 kDa subunit|TFIIH basal transcription factor complex helicase XPB subunit|TFIIH p89|basic transcription factor 2 89 kDa subunit|excision repair cross-complementing rodent repair deficiency, complementation group 3|xeroderma pigmentosum group B-complementing protein|xeroderma pigmentosum, complementation group B
Swissprots	Q53QM0 P19447
Accessions	AAN46739 AAY15069 EAW95311 EAW95312 EAW95313 EAW95314 P19447 AI222871 AK091500 BAG52374 AK095557 BAG53083 AK126697 AK127469 AK222465 BAD96185 AK290474 BAF83163 AK300250 BAG62016 AK307338 AK309405 BC008820 AAH08820 DQ893802 ABM84728 EU176179 ABW03630 M31899 AAA52396 XM_011510794 XP_011509096 XM_011510795 XP_011509097 NM_000122 NP_000113 NM_001303416 NP_001290345 NM_001303418 NP_001290347
Function	ATP-dependent 3'-5' DNA helicase, component of the core- TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage. {ECO:0000269|PubMed:10024882, ECO:0000269|PubMed:8157004}.
Subcellular Location	Nucleus.
Top Pathways	Nucleotide excision repair, Basal transcription factors

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

XPB (2C6) Mouse mAb - 8746 from Cell Signaling Technology Prices $99.00, $246.00 Sizes 20 µl (2 western blots), 100 µl (10 western blots) Host Mouse Clonality Monoclonal Clone 2C6

TFIIH p89 (G-10) - sc-271500 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

TFIIH p89 (B-7) - sc-377301 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

TFIIH p89 (S-19) - sc-293 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

TFIIH p89 (H-300) - sc-20697 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-XPB antibody - ab53198 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-XPB antibody [2327C4a] - ab70596 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2327C4a

Anti-ERCC3 / XPB Antibody - LS-C65568 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Mouse Clonality Monoclonal

Anti-ERCC3 / XPB Antibody (aa1-375) - LS-C144280 from LifeSpan Bioscience Prices $605.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-ERCC3 / XPB Antibody (aa732-782) - LS-C288147 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ERCC3 / XPB Antibody (N-Terminus) - LS-C116163 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ERCC3 / XPB Antibody (clone 2327C4a) - LS-C184639 from LifeSpan Bioscience Prices $335.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 2327C4a

Anti-ERCC3 / XPB Antibody (aa575-625) - LS-C288148 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ERCC3 / XPB Antibody - LS-C331648 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ERCC3 / XPB Antibody - LS-C109360 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ERCC3 / XPB Antibody (C-Terminus) IHC-plus™ - LS-B1693 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ERCC3 / XPB Antibody (aa242-261, clone 3G4) IHC-plus™ - LS-B2815 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 3G4

Anti-ERCC3 / XPB Antibody (clone 2327C4a) - LS-C342672 from LifeSpan Bioscience Prices $375.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2327C4a

Anti-ERCC3 / XPB Antibody (aa575-625) - LS-C286522 from LifeSpan Bioscience Prices $415.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

XPB Antibody - AF6349 from Novus Biologicals Prices $99.00, $359.00 Sizes 25 µg, 100 µg Host Goat Clonality Polyclonal

XPB Antibody - NB100-61059 from Novus Biologicals Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

XPB Antibody - NB100-61060 from Novus Biologicals Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

XPB Antibody - NBP1-31389 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

XPB Antibody - H00002071-A01 from Novus Biologicals Prices $269.00 Sizes 50 µl Host Mouse Clonality Polyclonal

XPB Polyclonal Antibody - bs-4260R from Bioss Prices $269.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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