ERCC3

Gene Symbol	ERCC3
Entrez Gene	2071
Alt Symbol	BTF2, GTF2H, RAD25, TFIIH, XPB
Species	Human
Gene Type	protein-coding
Description	excision repair cross-complementation group 3
Other Description	BTF2 p89|DNA excision repair protein ERCC-3|DNA repair helicase|DNA repair protein complementing XP-B cells|TFIIH 89 kDa subunit|TFIIH basal transcription factor complex 89 kDa subunit|TFIIH basal transcription factor complex helicase XPB subunit|TFIIH p89|basic transcription factor 2 89 kDa subunit|excision repair cross-complementing rodent repair deficiency, complementation group 3|xeroderma pigmentosum group B-complementing protein|xeroderma pigmentosum, complementation group B
Swissprots	Q53QM0 P19447
Accessions	AAN46739 AAY15069 EAW95311 EAW95312 EAW95313 EAW95314 P19447 AI222871 AK091500 BAG52374 AK095557 BAG53083 AK126697 AK127469 AK222465 BAD96185 AK290474 BAF83163 AK300250 BAG62016 AK307338 AK309405 BC008820 AAH08820 DQ893802 ABM84728 EU176179 ABW03630 M31899 AAA52396 XM_011510794 XP_011509096 XM_011510795 XP_011509097 NM_000122 NP_000113 NM_001303416 NP_001290345 NM_001303418 NP_001290347
Function	ATP-dependent 3'-5' DNA helicase, component of the core- TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage. {ECO:0000269|PubMed:10024882, ECO:0000269|PubMed:8157004}.
Subcellular Location	Nucleus.
Top Pathways	Nucleotide excision repair, Basal transcription factors

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human XPB full length protein - ab114794 from Abcam Category Protein Source Wheat germ Species Human

Human XPB peptide - ab30634 from Abcam Category Peptide

Human XPB protein fragment - ab114795 from Abcam Category Protein Source Wheat germ Species Human

ERCC3 / XPB Antibody Blocking Peptide - LS-E13612 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human XPB Protein - H00002071-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human XPB Protein - H00002071-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ERCC3-Antibody-N-term-Blocking-Peptide - BP17749a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ERCC3 - H00002071-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ERCC3 - H00002071-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ERCC3 - H00002071-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ERCC3 - H00002071-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ERCC3 fusion protein - ag20286 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

ERCC3 fusion protein - ag0876 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human ERCC3, His-tagged - ERCC3-2671H from Creative Biomart Category Protein Source E. coli .

Recombinant Human ERCC3 - ERCC3-30702TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human ERCC3 - ERCC3-30703TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human TFIIH basal transcription factor complex helicase XPB subunit(ERCC3) - CSB-YP007771HU CSB-EP007771HU CSB-BP007771HU CSB-MP007771HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TFIIH basal transcription factor complex helicase XPB subunit (ERCC3), Recombinant Protein - MBS951303 from MyBioSource Category Protein Prices $1,600.00, $1,600.00, $1,830.00, $1,830.00, $2,745.00, $2,745.00, $3,210.00, $3,210.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ERCC3 Peptide, Human - M34GP05035H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Xeroderma Pigmentosum, Complementation Group B (XPB) - RPU50728 from Biomatik Category Protein Prices $182.00, $315.00, $482.00, $602.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

XPB Recombinant Protein Antigen - NBP2-58758PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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