CHRNA10

Gene Symbol CHRNA10
Entrez Gene 57053
Alt Symbol -
Species Human
Gene Type protein-coding
Description cholinergic receptor, nicotinic, alpha 10 (neuronal)
Other Description NACHR alpha-10|acetylcholine receptor, nicotinic, alpha 10 (neuronal)|cholinergic receptor, nicotinic, alpha polypeptide 10|neuronal acetylcholine receptor subunit alpha-10|nicotinic acetylcholine receptor subunit alpha-10
Swissprots Q9GZZ6
Accessions AAK14333 EAX02560 Q9GZZ6 AF199235 AAG00795 AJ278118 CAC20435 AJ295237 CAC16144 BC136250 AAI36251 BC143303 BC152764 AAI52765 XM_011520234 XP_011518536 NM_001303034 NP_001289963 NM_001303035 NP_001289964 NM_020402 NP_065135
Function Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. {ECO:0000269|PubMed:11752216}.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes. {ECO:0000269|PubMed:11752216, ECO:0000269|PubMed:15531379}.
Top Pathways Neuroactive ligand-receptor interaction

AChRα10 (H-73) - sc-368613 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

AChRα10 (N-18) - sc-18277 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CHRNA10 antibody - ab170602 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CHRNA10 antibody (ab170602) at 1/100 dilutionLane 1 : NCI-H292 cell line lysateLane 2 : MDA-MB453 cell line lysateLane 3 : ZR-75-1 cell line lysateLysates/proteins at 35 µg per lane.

Anti-CHRNA10 antibody - ab110063 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CHRNA10 antibody (ab110063) at 1/500 dilutionLane 1 : Extracts from A549 cellsLane 2 : Extracts from COLO cellsLane 3 : Extracts from 293 cellsLane 4 : Extracts from HeLa cellsLane 5 : Extracts from A549 cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-CHRNA10 Antibody (aa186-214, AP) - LS-C221775 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNA10 Antibody (aa186-214, APC) - LS-C221776 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNA10 Antibody (aa186-214, FITC) - LS-C221778 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNA10 Antibody (aa186-214, Biotin) - LS-C221777 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNA10 Antibody (aa186-214, PE) - LS-C221780 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNA10 Antibody (aa186-214, Azide-free, HRP) - LS-C221779 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNA10 Antibody (aa186-214) - LS-C320369 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNA10 Antibody (N-Terminus) - LS-C345634 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of CHRNA10 Antibody with human 721_B Whole Cell lysate.

Anti-CHRNA10 Antibody (aa186-214) - LS-C168752 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CHRNA10 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human tonsil tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CHRNA10 Antibody (aa394-443) IHC-plus™ - LS-B9850 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CHRNA10 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9850 concentration 10 ug/ml.

Nicotinic Acetylcholine R alpha 10/CHRNA10 Antibody - NBP2-32574 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Immunohistochemistry: CHRNA10 Antibody [NBP2-32574] - parathyroid gland

Nicotinic Acetylcholine R alpha 10/CHRNA10 Antibody - NBP1-46573 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CHRNA10 Polyclonal Antibody - bs-12111R from Bioss

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CHRNA10 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12111R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CHRNA10 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12111R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CHRNA10 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12111R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CHRNA10 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12111R-A647 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CHRNA10 Polyclonal Antibody, Cy3 Conjugated - bs-12111R-Cy3 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CHRNA10 Polyclonal Antibody, Cy5 Conjugated - bs-12111R-Cy5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CHRNA10 Polyclonal Antibody, Cy5.5 Conjugated - bs-12111R-Cy5.5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CHRNA10 Polyclonal Antibody, Cy7 Conjugated - bs-12111R-Cy7 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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