| Gene Symbol |
CYP4F12
|
| Entrez Gene |
66002
|
| Alt Symbol |
CYPIVF12, F22329_1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 4, subfamily F, polypeptide 12
|
| Other Description |
cytochrome P450 4F12|cytochrome P450, subfamily IVF, polypeptide 12
|
| Swissprots |
Q9HCS1 O60389 Q5JPJ7 Q9HCS2 E7ET51
|
| Accessions |
AAC11543 AAS49383 AAS49384 AAS49385 AAS49386 EAW84492 EAW84493 EAW84494 EAW84495 EAW84496 EAW84497 EAW84498 EAW84499 EAW84500 EAW84501 Q9HCS2 AB035130 BAB18269 AB035131 BAB18270 AK074412 AK075435 BAG52137 AK304138 BAG65032 AK304389 BAG65224 AL832171 CAI46131 AY008841 AAG33247 AY358977 AAQ89336 BC034916 BC035350 AAH35350 DB016100 DB221158 DC418592 DQ890810 ABM81736 DQ893965 ABM84891 DR422336 XM_006722850 XP_006722913 XM_011528199 XP_011526501 XM_011528200 XP_011526502 XM_011528201 XP_011526503 XM_011528202 XP_011526504 XM_011528203 XP_011526505 XM_011528204 XP_011526506 XM_011528205 XP_011526507 XM_011528206 XP_011526508 XM_011528207 XP_011526509 XM_011528208 XP_011526510 NM_023944 NP_076433 NR_117085
|
| Function |
Catalyzes leukotriene B4 omega-hydroxylation and arachidonic acid omega-hydroxylation but with an activity much lower than that of CYP4F2. Catalyzes the hydroxylation of the antihistamine ebastine.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed in small intestine, liver, colon and heart. {ECO:0000269|PubMed:11162607, ECO:0000269|PubMed:11162645}.
|