| Gene Symbol |
SLC28A2
|
| Entrez Gene |
9153
|
| Alt Symbol |
CNT2, HCNT2, HsT17153, SPNT1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 28 (concentrative nucleoside transporter), member 2
|
| Other Description |
CNT 2|Na(+)/nucleoside cotransporter 2|SPNT|concentrative nucleoside transporter 2|sodium-coupled nucleoside transporter 2|sodium/nucleoside cotransporter 2|sodium/purine nucleoside co-transporter|solute carrier family 28 (sodium-coupled nucleoside transporter), member 2|solute carrier family 28 member 2
|
| Swissprots |
A8K7F9 O43868 Q52LZ0 O43239
|
| Accessions |
EAW77303 EAW77304 O43868 AF036109 AAB88539 AK025121 AK222709 BAD96429 AK291974 BAF84663 BC093737 AAH93737 BC112047 AAI12048 U84392 AAC51930 XM_011522198 XP_011520500 XM_011522199 XP_011520501 XM_011522200 XP_011520502 XM_011522201 XP_011520503 XM_011522202 XP_011520504 NM_004212 NP_004203
|
| Function |
Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung.
|