Gene Symbol | SLC28A2 |
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Entrez Gene | 9153 |
Alt Symbol | CNT2, HCNT2, HsT17153, SPNT1 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 28 (concentrative nucleoside transporter), member 2 |
Other Description | CNT 2|Na(+)/nucleoside cotransporter 2|SPNT|concentrative nucleoside transporter 2|sodium-coupled nucleoside transporter 2|sodium/nucleoside cotransporter 2|sodium/purine nucleoside co-transporter|solute carrier family 28 (sodium-coupled nucleoside transporter), member 2|solute carrier family 28 member 2 |
Swissprots | A8K7F9 O43868 Q52LZ0 O43239 |
Accessions | EAW77303 EAW77304 O43868 AF036109 AAB88539 AK025121 AK222709 BAD96429 AK291974 BAF84663 BC093737 AAH93737 BC112047 AAI12048 U84392 AAC51930 XM_011522198 XP_011520500 XM_011522199 XP_011520501 XM_011522200 XP_011520502 XM_011522201 XP_011520503 XM_011522202 XP_011520504 NM_004212 NP_004203 |
Function | Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung. |
CNT2 CRISPR/Cas9 KO Plasmid (h) - sc-409209 from Santa Cruz Biotechnology
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CNT2 HDR Plasmid (h) - sc-409209-HDR from Santa Cruz Biotechnology
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CNT2 Double Nickase Plasmid (h) - sc-409209-NIC from Santa Cruz Biotechnology
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CNT2 Double Nickase Plasmid (h2) - sc-409209-NIC-2 from Santa Cruz Biotechnology
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CNT2 CRISPR Activation Plasmid (h) - sc-409209-ACT from Santa Cruz Biotechnology
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CNT2 CRISPR Activation Plasmid (h2) - sc-409209-ACT-2 from Santa Cruz Biotechnology
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CNT2 Lentiviral Activation Particles (h) - sc-409209-LAC from Santa Cruz Biotechnology
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CNT2 Lentiviral Activation Particles (h2) - sc-409209-LAC-2 from Santa Cruz Biotechnology
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CNT2 siRNA (h) - sc-60423 from Santa Cruz Biotechnology
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CNT2 shRNA Plasmid (h) - sc-60423-SH from Santa Cruz Biotechnology
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CNT2 shRNA (h) Lentiviral Particles - sc-60423-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN19538 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19538 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03726 from Sigma-Aldrich
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SLC28A2 siRNA (Human) - CRH6058 from Cohesion Biosciences
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SLC28A2 RNAi - H00009153-R01 from Novus Biologicals
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SLC28A2 - MBS8205755 from MyBioSource
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shRNA set against Human SLC28A2 (NM_004212.3) - SHH410124 from Creative biogene
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Human SLC28A2 siRNA - orb266560 from Biorbyt
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SLC28A2 shRNA Plasmid (Human) - CHH6058 from Cohesion Biosciences
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SLC28A2 miRNA 3'UTR clone - MiUTR4H-TG08232 from Creative biogene
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