| Gene Symbol |
CALY
|
| Entrez Gene |
50632
|
| Alt Symbol |
DRD1IP, NSG3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
calcyon neuron-specific vesicular protein
|
| Other Description |
D1 dopamine receptor-interacting protein|calcyon D1 dopamine receptor-interacting protein (CALCYON)|calcyon protein|dopamine receptor D1 interacting protein|neuron-specific vesicular protein calcyon
|
| Swissprots |
Q5VWX3 Q5VWY6 Q9NYX4 Q5VWY5
|
| Accessions |
EAW61334 EAW61335 Q9NYX4 AF225903 AAF34714 BC038978 AAH38978 BI914942 BP392207 HG503392 XM_005252685 XP_005252742 XM_011539835 XP_011538137 XM_011539836 XP_011538138 XM_011539837 XP_011538139 XM_011539838 XP_011538140 XM_011539839 XP_011538141 NM_015722 NP_056537
|
| Function |
Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. {ECO:0000269|PubMed:16595675}.
|
| Subcellular Location |
Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.
|
| Tissue Specificity |
Expressed in the pyramidal cells of the prefrontal cortex, in hippothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non- schizophrenics. {ECO:0000269|PubMed:12622665}.
|
| Top Pathways |
Dopaminergic synapse
|