| Gene Symbol | HIST1H2AJ |
|---|---|
| Entrez Gene | 8331 |
| Alt Symbol | H2A/E, H2AFE, dJ160A22.4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | histone cluster 1, H2aj |
| Other Description | H2A histone family, member E|histone 1, H2aj |
| Swissprots | Q5JXQ5 A2RUU6 Q99878 |
| Accessions | AAN59971 CAB06031 EAX03109 BC066232 AAH66232 BC066233 AAH66233 BC066234 AAH66234 BC066235 AAH66235 BC066236 AAH66236 BC066237 AAH66237 BC133048 AAI33049 BC133050 AAI33051 HQ447447 ADQ31933 NM_021066 NP_066544 |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Subcellular Location | Nucleus. Chromosome. |
| Top Pathways | Systemic lupus erythematosus, Alcoholism |
histone cluster 1, H2aj, ELISA Kit - MBS9343145 from MyBioSource
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Human HIST1H2AJ ELISA Kit - E018758 from Biobool
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