| Gene Symbol |
HIST1H2AJ
|
| Entrez Gene |
8331
|
| Alt Symbol |
H2A/E, H2AFE, dJ160A22.4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 1, H2aj
|
| Other Description |
H2A histone family, member E|histone 1, H2aj
|
| Swissprots |
Q5JXQ5 A2RUU6 Q99878
|
| Accessions |
AAN59971 CAB06031 EAX03109 BC066232 AAH66232 BC066233 AAH66233 BC066234 AAH66234 BC066235 AAH66235 BC066236 AAH66236 BC066237 AAH66237 BC133048 AAI33049 BC133050 AAI33051 HQ447447 ADQ31933 NM_021066 NP_066544
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Top Pathways |
Systemic lupus erythematosus, Alcoholism
|