Gene Symbol | HIST1H2AJ |
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Entrez Gene | 8331 |
Alt Symbol | H2A/E, H2AFE, dJ160A22.4 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2aj |
Other Description | H2A histone family, member E|histone 1, H2aj |
Swissprots | Q5JXQ5 A2RUU6 Q99878 |
Accessions | AAN59971 CAB06031 EAX03109 BC066232 AAH66232 BC066233 AAH66233 BC066234 AAH66234 BC066235 AAH66235 BC066236 AAH66236 BC066237 AAH66237 BC133048 AAI33049 BC133050 AAI33051 HQ447447 ADQ31933 NM_021066 NP_066544 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Alcoholism |
Histone cluster 1 H2AJ CRISPR/Cas9 KO Plasmid (h) - sc-418137 from Santa Cruz Biotechnology
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Histone cluster 1 H2AJ HDR Plasmid (h) - sc-418137-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H2AJ Double Nickase Plasmid (h) - sc-418137-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H2AJ Double Nickase Plasmid (h2) - sc-418137-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2AJ CRISPR Activation Plasmid (h) - sc-418137-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H2AJ CRISPR Activation Plasmid (h2) - sc-418137-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2AJ Lentiviral Activation Particles (h) - sc-418137-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H2AJ Lentiviral Activation Particles (h2) - sc-418137-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2AJ siRNA (h) - sc-105467 from Santa Cruz Biotechnology
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Histone cluster 1 H2AJ shRNA Plasmid (h) - sc-105467-SH from Santa Cruz Biotechnology
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Histone cluster 1 H2AJ shRNA (h) Lentiviral Particles - sc-105467-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10064 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10064 from Sigma-Aldrich
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HIST1H2AJ siRNA (Human) - CRH5452 from Cohesion Biosciences
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HIST1H2AJ - MBS8225426 from MyBioSource
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shRNA set against Human HIST1H2AJ (NM_021066.2) - SHH312505 from Creative biogene
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HIST1H2AJ shRNA Plasmid (Human) - CHH5452 from Cohesion Biosciences
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HIST1H2AJ miRNA 3'UTR clone - MiUTR1H-04526 from Creative biogene
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