PDZD3

Gene Symbol	PDZD3
Entrez Gene	79849
Alt Symbol	IKEPP, NHERF4, PDZK2
Species	Human
Gene Type	protein-coding
Description	PDZ domain containing 3
Other Description	NHERF-4|Na(+)/H(+) exchange regulatory cofactor NHE-RF4|PDZ domain containing 2|PDZ domain-containing protein 2|PDZ domain-containing protein 3|intestinal and kidney enriched PDZ protein|intestinal and kidney-enriched PDZ protein|na/Pi cotransporter C-terminal-associated protein 2|naPi-Cap2|natrium-phosphate cotransporter IIa C-terminal-associated protein 2|sodium-hydrogen exchanger regulatory factor 4
Swissprots	Q8NEX7 Q8NAW7 Q8N6R4 Q9H5Z3 Q86UT5
Accessions	ACA06039 EAW67470 EAW67471 EAW67472 EAW67473 EAW67474 Q86UT5 AB094096 BAC76050 AK026409 BAB15474 AK091966 BAC03780 AK298333 BAG60582 AK315403 AY047359 AAL10686 BC029042 AAH29042 BX648391 DA381610 XM_011543000 XP_011541302 XM_011543001 XP_011541303 XM_011543002 XP_011541304 XM_011543003 XP_011541305 XM_011543004 XP_011541306 XM_011543005 XP_011541307 XM_011543006 XP_011541308 XM_011543007 XP_011541309 XM_011543008 XP_011541310 NM_001168468 NP_001161940 NM_024791 NP_079067 NR_033122
Function	Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions. {ECO:0000269|PubMed:11950846, ECO:0000269|PubMed:19088451}.
Subcellular Location	Cell membrane; Peripheral membrane protein. Cytoplasm. Note=Preferentially accumulates at the apical surface and ileal brush border of intestinal epithelial cells.
Tissue Specificity	Expressed in kidney and the gastrointestinal tract. Not detected in brain, heart, skeletal muscle or cells of hematopoietic origin. {ECO:0000269|PubMed:11950846}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Na (+)/H (+) exchange regulatory cofactor NHE-RF4 (PDZD3), Human, ELISA Kit - CSB-EL017753HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

PDZD3 (Human) IP-WB Antibody Pair - H00079849-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

PDZD3 (Human) Matched Antibody Pair - H00079849-AP21 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

PDZ domain containing 3, ELISA Kit - MBS909831 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human PDZD3 is typically less than 3.9 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 15.6 pg/ml -1000 pg/ml.

Human Na(+)/H(+) exchange regulatory cofactor NHE-RF4 (PDZD3) ELISA kit - CSB-EL017753HU from Cusabio Category ELISA Kit Sensitivity 3.9pg/ml Range 15.6 pg/ml-1000 pg/ml

Human PDZD3 ELISA Kit - E028462 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human PDZD3 is typically less than 3.9 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mea

PDZD3 ELISA Kit (Human) (OKCA01375) - OKCA01375 from Aviva Systems Biology Category ELISA Kit Prices $600.00 Sizes 96 wells Sensitivity 3.9 pg/mL Range 15.6 - 1,000 pg/mL

Human PDZD3 ELISA Kit - orb404890 from Biorbyt Category ELISA Kit Sensitivity 3.9pg/ml Range 15.6 pg/ml-1000 pg/ml

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