PDZD3

Gene Symbol	PDZD3
Entrez Gene	79849
Alt Symbol	IKEPP, NHERF4, PDZK2
Species	Human
Gene Type	protein-coding
Description	PDZ domain containing 3
Other Description	NHERF-4|Na(+)/H(+) exchange regulatory cofactor NHE-RF4|PDZ domain containing 2|PDZ domain-containing protein 2|PDZ domain-containing protein 3|intestinal and kidney enriched PDZ protein|intestinal and kidney-enriched PDZ protein|na/Pi cotransporter C-terminal-associated protein 2|naPi-Cap2|natrium-phosphate cotransporter IIa C-terminal-associated protein 2|sodium-hydrogen exchanger regulatory factor 4
Swissprots	Q8NEX7 Q8NAW7 Q8N6R4 Q9H5Z3 Q86UT5
Accessions	ACA06039 EAW67470 EAW67471 EAW67472 EAW67473 EAW67474 Q86UT5 AB094096 BAC76050 AK026409 BAB15474 AK091966 BAC03780 AK298333 BAG60582 AK315403 AY047359 AAL10686 BC029042 AAH29042 BX648391 DA381610 XM_011543000 XP_011541302 XM_011543001 XP_011541303 XM_011543002 XP_011541304 XM_011543003 XP_011541305 XM_011543004 XP_011541306 XM_011543005 XP_011541307 XM_011543006 XP_011541308 XM_011543007 XP_011541309 XM_011543008 XP_011541310 NM_001168468 NP_001161940 NM_024791 NP_079067 NR_033122
Function	Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions. {ECO:0000269|PubMed:11950846, ECO:0000269|PubMed:19088451}.
Subcellular Location	Cell membrane; Peripheral membrane protein. Cytoplasm. Note=Preferentially accumulates at the apical surface and ileal brush border of intestinal epithelial cells.
Tissue Specificity	Expressed in kidney and the gastrointestinal tract. Not detected in brain, heart, skeletal muscle or cells of hematopoietic origin. {ECO:0000269|PubMed:11950846}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PDZD3 293T Cell Transient Overexpression Lysate(Denatured) - H00079849-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

PDZD3 overexpression lysate - LY433192 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PDZD3 293 Cell Lysate - 402635 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

IKEPP Overexpression Lysate (Denatured) - H00079849-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

IKEPP Overexpression Lysate (Native) - NBL1-14270 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PDZD3 Over-expression Lysate Product - GWB-53DD93 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

IKEPP Overexpression Lysate (Denatured) - H00079849-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human PDZD3 Knockdown Stable Cell Line - CSC-DC011565 from Creative biogene Category Cell Line Species Human

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