PDZD3

Gene Symbol	PDZD3
Entrez Gene	79849
Alt Symbol	IKEPP, NHERF4, PDZK2
Species	Human
Gene Type	protein-coding
Description	PDZ domain containing 3
Other Description	NHERF-4|Na(+)/H(+) exchange regulatory cofactor NHE-RF4|PDZ domain containing 2|PDZ domain-containing protein 2|PDZ domain-containing protein 3|intestinal and kidney enriched PDZ protein|intestinal and kidney-enriched PDZ protein|na/Pi cotransporter C-terminal-associated protein 2|naPi-Cap2|natrium-phosphate cotransporter IIa C-terminal-associated protein 2|sodium-hydrogen exchanger regulatory factor 4
Swissprots	Q8NEX7 Q8NAW7 Q8N6R4 Q9H5Z3 Q86UT5
Accessions	ACA06039 EAW67470 EAW67471 EAW67472 EAW67473 EAW67474 Q86UT5 AB094096 BAC76050 AK026409 BAB15474 AK091966 BAC03780 AK298333 BAG60582 AK315403 AY047359 AAL10686 BC029042 AAH29042 BX648391 DA381610 XM_011543000 XP_011541302 XM_011543001 XP_011541303 XM_011543002 XP_011541304 XM_011543003 XP_011541305 XM_011543004 XP_011541306 XM_011543005 XP_011541307 XM_011543006 XP_011541308 XM_011543007 XP_011541309 XM_011543008 XP_011541310 NM_001168468 NP_001161940 NM_024791 NP_079067 NR_033122
Function	Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions. {ECO:0000269|PubMed:11950846, ECO:0000269|PubMed:19088451}.
Subcellular Location	Cell membrane; Peripheral membrane protein. Cytoplasm. Note=Preferentially accumulates at the apical surface and ileal brush border of intestinal epithelial cells.
Tissue Specificity	Expressed in kidney and the gastrointestinal tract. Not detected in brain, heart, skeletal muscle or cells of hematopoietic origin. {ECO:0000269|PubMed:11950846}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PDZD3 full length protein - ab164137 from Abcam Category Protein Source Wheat germ Species Human

PDZD3 Antibody Blocking Peptide - LS-E5202 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IKEPP Protein - H00079849-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PDZD3-Antibody-Center-Blocking-Peptide - BP17639c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PDZD3 - H00079849-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PDZD3 - H00079849-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PDZD3 fusion protein - ag6931 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

PDZD3 fusion protein - ag3956 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Na(+)/H(+) exchange regulatory cofactor NHE-RF4(PDZD3) - CSB-YP774807HU CSB-EP774807HU CSB-BP774807HU CSB-MP774807HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PDZD3 Peptide, Human - M34GP11565H from Creative Peptides Category Peptide Source Synthetic. Species Human

Na (+) /H (+) exchange regulatory cofactor NHE-RF4 (PDZD3), Recombinant Protein - MBS1282969 from MyBioSource Category Protein Prices $1,370.00, $1,370.00, $1,585.00, $1,585.00, $2,280.00, $2,280.00, $2,740.00, $2,740.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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