PDZD3

Gene Symbol PDZD3
Entrez Gene 79849
Alt Symbol IKEPP, NHERF4, PDZK2
Species Human
Gene Type protein-coding
Description PDZ domain containing 3
Other Description NHERF-4|Na(+)/H(+) exchange regulatory cofactor NHE-RF4|PDZ domain containing 2|PDZ domain-containing protein 2|PDZ domain-containing protein 3|intestinal and kidney enriched PDZ protein|intestinal and kidney-enriched PDZ protein|na/Pi cotransporter C-terminal-associated protein 2|naPi-Cap2|natrium-phosphate cotransporter IIa C-terminal-associated protein 2|sodium-hydrogen exchanger regulatory factor 4
Swissprots Q8NEX7 Q8NAW7 Q8N6R4 Q9H5Z3 Q86UT5
Accessions ACA06039 EAW67470 EAW67471 EAW67472 EAW67473 EAW67474 Q86UT5 AB094096 BAC76050 AK026409 BAB15474 AK091966 BAC03780 AK298333 BAG60582 AK315403 AY047359 AAL10686 BC029042 AAH29042 BX648391 DA381610 XM_011543000 XP_011541302 XM_011543001 XP_011541303 XM_011543002 XP_011541304 XM_011543003 XP_011541305 XM_011543004 XP_011541306 XM_011543005 XP_011541307 XM_011543006 XP_011541308 XM_011543007 XP_011541309 XM_011543008 XP_011541310 NM_001168468 NP_001161940 NM_024791 NP_079067 NR_033122
Function Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions. {ECO:0000269|PubMed:11950846, ECO:0000269|PubMed:19088451}.
Subcellular Location Cell membrane; Peripheral membrane protein. Cytoplasm. Note=Preferentially accumulates at the apical surface and ileal brush border of intestinal epithelial cells.
Tissue Specificity Expressed in kidney and the gastrointestinal tract. Not detected in brain, heart, skeletal muscle or cells of hematopoietic origin. {ECO:0000269|PubMed:11950846}.

PDZK2 CRISPR/Cas9 KO Plasmid (h) - sc-407977 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDZK2 HDR Plasmid (h) - sc-407977-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDZK2 Double Nickase Plasmid (h) - sc-407977-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDZK2 Double Nickase Plasmid (h2) - sc-407977-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDZK2 CRISPR Activation Plasmid (h) - sc-407977-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDZK2 CRISPR Activation Plasmid (h2) - sc-407977-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDZK2 Lentiviral Activation Particles (h) - sc-407977-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDZK2 Lentiviral Activation Particles (h2) - sc-407977-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDZK2 siRNA (h) - sc-76102 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PDZK2 shRNA Plasmid (h) - sc-76102-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PDZK2 shRNA (h) Lentiviral Particles - sc-76102-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IKEPP RNAi - H00079849-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU068381 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16592 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16592 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PDZD3 siRNA (Human) - CRJ2613 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PDZD3 (NM_024791.3) - SHH373200 from Creative biogene

Category siRNA
Species Reactivities Human

Human PDZD3 siRNA - orb273114 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PDZD3 shRNA Plasmid (Human) - CHJ2613 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PDZD3 miRNA 3'UTR clone - MiUTR3H-09004 from Creative biogene

Species Reactivities Human
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