TPM2

Gene Symbol	TPM2
Entrez Gene	7169
Alt Symbol	AMCD1, DA1, DA2B, HEL-S-273, NEM4, TMSB
Species	Human
Gene Type	protein-coding
Description	tropomyosin 2 (beta)
Other Description	epididymis secretory protein Li 273|nemaline myopathy type 4|tropomyosin beta chain
Swissprots	Q9UH67 P06468 P07951 Q5TCU7 Q13894 A6NM85 Q5TCU4 Q53FM4
Accessions	AAA51842 AAF17621 EAW58354 EAW58355 P07951 AA394062 AI360640 AI660199 AJ572605 AK130045 AK223258 BAD96978 AK294522 BAG57733 AK300249 BAG62015 AK304803 BAG65553 BC011776 AAH11776 BE294047 DQ892908 ABM83834 DQ896159 ABM87158 EU106177 ABU62930 F24979 FJ224304 ACI45996 M12125 AAA36773 M12126 AAA61229 M74817 AAA61230 M75165 AAB59509 X06825 CAA29971 XR_929320 XR_929321 XR_929322 XR_929323 XR_929324 XR_929325 NM_001301226 NP_001288155 NM_001301227 NP_001288156 NM_003289 NP_003280 NM_213674 NP_998839 NM_001145822
Function	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytoskeleton.
Tissue Specificity	Present in primary breast cancer tissue, absent from normal breast tissue. {ECO:0000269|Ref.10}.
Top Pathways	Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Tropomyosin β (J-23) - sc-134128 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

Anti-Tropomyosin 2 antibody - ab180866 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Tropomyosin 2 antibody [EPR12845] - ab187165 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR12845

Anti-Tropomyosin 2 antibody [EPR12846] - C-terminal - ab180176 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR12846

Anti-TPM2 Antibody (clone ST-39, Sepharose) - LS-C171004 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone ST-39

Anti-TPM2 Antibody (aa252-280, AP) - LS-C272012 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (aa252-280, APC) - LS-C272013 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (aa252-280, Biotin) - LS-C272014 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (aa252-280, FITC) - LS-C272015 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (aa252-280, Azide-free, HRP) - LS-C272016 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (aa252-280, PE) - LS-C272017 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (Biotin) - LS-C317013 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody - LS-C285725 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (aa251-280) - LS-C325889 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (HRP) - LS-C317015 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (FITC) - LS-C317014 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (C-Terminus) - LS-C81187 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody - LS-C341539 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (clone 3C8) - LS-C133962 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3C8

Anti-TPM2 Antibody (aa1-234) - LS-C186058 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody (aa252-280) - LS-C157249 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody - LS-C332358 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-TPM2 Antibody - LS-C122501 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-TPM2 Antibody - LS-C124706 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-TPM2 Antibody - LS-C132679 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Search more