TPM2

Gene Symbol	TPM2
Entrez Gene	7169
Alt Symbol	AMCD1, DA1, DA2B, HEL-S-273, NEM4, TMSB
Species	Human
Gene Type	protein-coding
Description	tropomyosin 2 (beta)
Other Description	epididymis secretory protein Li 273|nemaline myopathy type 4|tropomyosin beta chain
Swissprots	Q9UH67 P06468 P07951 Q5TCU7 Q13894 A6NM85 Q5TCU4 Q53FM4
Accessions	AAA51842 AAF17621 EAW58354 EAW58355 P07951 AA394062 AI360640 AI660199 AJ572605 AK130045 AK223258 BAD96978 AK294522 BAG57733 AK300249 BAG62015 AK304803 BAG65553 BC011776 AAH11776 BE294047 DQ892908 ABM83834 DQ896159 ABM87158 EU106177 ABU62930 F24979 FJ224304 ACI45996 M12125 AAA36773 M12126 AAA61229 M74817 AAA61230 M75165 AAB59509 X06825 CAA29971 XR_929320 XR_929321 XR_929322 XR_929323 XR_929324 XR_929325 NM_001301226 NP_001288155 NM_001301227 NP_001288156 NM_003289 NP_003280 NM_213674 NP_998839 NM_001145822
Function	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytoskeleton.
Tissue Specificity	Present in primary breast cancer tissue, absent from normal breast tissue. {ECO:0000269|Ref.10}.
Top Pathways	Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat TPM2 ELISA Kit (Sandwich ELISA) - LS-F8461 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.119 ng/ml Range 0.313-20 ng/ml

Tropomyosin beta chain (TPM2), Human, ELISA Kit - CSB-EL024105HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Tropomyosin beta chain (TPM2), Human, ELISA Kit - E01T0729 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

tropomyosin 2 (beta) , ELISA Kit - MBS908144 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human TPM2 is typically less than 9.77 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 39.07 pg/ml -2500 pg/ml.

Tropomyosin 2 Beta, ELISA Kit - MBS103188 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS102941 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS100126 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS076066 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS054855 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS073037 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS080717 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS090447 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS101972 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS051550 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS070500 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS057980 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS080555 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS063936 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS057805 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS081625 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS049390 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS084218 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta, ELISA Kit - MBS071422 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin 2 Beta (TPM2), ELISA Kit - MBS2022093 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.119ng/mL. Range 0.313-20ng/mL

Tropomyosin beta chain (TPM2), ELISA Kit - MBS7218949 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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