TPM2

Gene Symbol	TPM2
Entrez Gene	7169
Alt Symbol	AMCD1, DA1, DA2B, HEL-S-273, NEM4, TMSB
Species	Human
Gene Type	protein-coding
Description	tropomyosin 2 (beta)
Other Description	epididymis secretory protein Li 273|nemaline myopathy type 4|tropomyosin beta chain
Swissprots	Q9UH67 P06468 P07951 Q5TCU7 Q13894 A6NM85 Q5TCU4 Q53FM4
Accessions	AAA51842 AAF17621 EAW58354 EAW58355 P07951 AA394062 AI360640 AI660199 AJ572605 AK130045 AK223258 BAD96978 AK294522 BAG57733 AK300249 BAG62015 AK304803 BAG65553 BC011776 AAH11776 BE294047 DQ892908 ABM83834 DQ896159 ABM87158 EU106177 ABU62930 F24979 FJ224304 ACI45996 M12125 AAA36773 M12126 AAA61229 M74817 AAA61230 M75165 AAB59509 X06825 CAA29971 XR_929320 XR_929321 XR_929322 XR_929323 XR_929324 XR_929325 NM_001301226 NP_001288155 NM_001301227 NP_001288156 NM_003289 NP_003280 NM_213674 NP_998839 NM_001145822
Function	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytoskeleton.
Tissue Specificity	Present in primary breast cancer tissue, absent from normal breast tissue. {ECO:0000269|Ref.10}.
Top Pathways	Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Tropomyosin 2 full length protein - ab103503 from Abcam Category Protein Source E. coli Species Human

Human Tropomyosin 2 full length protein - ab88139 from Abcam Category Protein Source Saccharomyces cerevisiae Species Human

TPM2 Antibody Blocking Peptide - LS-E5122 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

tropomyosin-2 Recombinant Protein - H00007169-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 25 ug 10 ug Species Human

Recombinant Human tropomyosin-2 Protein - NBP1-50957 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 10 µg, 50 µg Source E. coli Species Human

TPM2-Antibody-C-term-Blocking-Peptide - BP17546b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Tropomyosin 2 Protein - GTX109268-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

Recombinant human Tropomyosin beta chain (OPCA00989) - OPCA00989 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

TPM2 Protein (OPPA02534) - OPPA02534 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 1 µg Source E. Coli

Human TPM2 protein - orb169465 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 1 μg, 5 μg, 50 μg Source E. coli

Human TMSB protein - orb245558 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

TPM2 protein - 30R-3268 from Fitzgerald Category Protein Prices $210.00 Sizes 50 µg Source E.coli

TPM2 protein (His tag) - 80R-1632 from Fitzgerald Category Protein Prices $295.00 Sizes 10 µg Source E.coli

Human TPM2 Protein - abx060014 from Abbexa Category Protein Source Yeast Species Human

TPM2 - H00007169-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

Tropomyosin-2 (TPM2) (1-284, His-tag) - AR09813PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 50 µg Source E. coli Species Human

Tropomyosin-2 (TPM2) (1-284, His-tag) - AR09813PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Source E. coli Species Human

TPM2, 1-284aa, Human, His tag, E.coli - 01-1919-2 from ARP American Research Products Category Protein Prices $159.00, $369.00, $849.00 Sizes 2 µg, 10 µg, 50 µg Species Human

TPM2 fusion protein - ag17362 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

TPM2 fusion protein - Ag1508 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

TPM2 Human - PRPS-076 from NeoScientific Category Protein Prices $65.00, $169.00, $1,560.00 Sizes 1 µg, 5 µg, 50 µg Source Escherichia Coli. Species Human

TPM2, 1-284aa, Recombinant Protein - GWB-P1165H from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 10 μg, 50 μg Source E.coli Species Human

TPM2 Human Protein - GWB-BSP696 from Genway Biotech Category Protein Prices $75.00, $165.00, $1,435.00 Sizes 1 μg, 5 μg, 50 μg Source Escherichia Coli. Species Human

Recombinant Human TPM2, His-tagged - TPM2-3442H from Creative Biomart Category Protein

Recombinant Human TPM2, His-tagged - TPM2-31626TH from Creative Biomart Category Protein Source E. coli

Search more