Gene Symbol | GABRG2 |
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Entrez Gene | 2566 |
Alt Symbol | CAE2, ECA2, GEFSP3 |
Species | Human |
Gene Type | protein-coding |
Description | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
Other Description | GABA(A) receptor subunit gamma-2|GABA(A) receptor, gamma 2|gamma-aminobutyric acid receptor subunit gamma-2 |
Swissprots | Q6GRL6 Q9UN15 P18507 Q9UDB3 F5HB82 Q6PCC3 |
Accessions | AAD50273 EAW61532 EAW61533 EAW61534 EAW61535 P18507 AK123394 AK299640 BAG61563 AK315200 BC036030 BC052926 BC059389 AAH59389 BC069348 AAH69348 BC074795 AAH74795 CD013896 CD013897 DA226729 X15376 CAA33437 NM_000816 NP_000807 NM_198903 NP_944493 NM_198904 NP_944494 |
Function | Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel. {ECO:0000269|PubMed:2538761}. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane {ECO:0000269|PubMed:2538761}; Multi-pass membrane protein {ECO:0000269|PubMed:2538761}. Cell membrane {ECO:0000269|PubMed:2538761}; Multi-pass membrane protein {ECO:0000269|PubMed:2538761}. |
Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |
GABA A Rγ2 (E-13) - sc-131934 from Santa Cruz Biotechnology
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GABA A Rγ2 (G-14) - sc-131935 from Santa Cruz Biotechnology
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GABA A Rγ2 (Q-18) - sc-101963 from Santa Cruz Biotechnology
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p-GABA A Rγ2 (Ser 365) - sc-135693 from Santa Cruz Biotechnology
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Anti-GABA A Receptor gamma 2 antibody - ab170224 from Abcam
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Anti-GABA A Receptor gamma 2 antibody - ab181667 from Abcam
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Anti-GABRG2 Antibody - LS-C14 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (aa205-232, AP) - LS-C214534 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (aa205-232, FITC) - LS-C214536 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (aa205-232, Biotin) - LS-C214537 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (aa205-232, APC) - LS-C214535 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (phospho-Ser327) - LS-C61868 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (aa205-232, Azide-free, HRP) - LS-C214538 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (aa400-410) - LS-C112991 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (aa36-85) - LS-C102839 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (aa205-232) - LS-C321529 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (aa205-232, PE) - LS-C214540 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (Cytoplasmic Domain) - LS-C201 from LifeSpan Bioscience
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Anti-GABRG2 Antibody - LS-C193027 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (Internal) - LS-C112965 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (aa198-224) - LS-C166330 from LifeSpan Bioscience
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Anti-GABRG2 Antibody - LS-C331661 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (aa61-110) IHC-plus⢠- LS-B11464 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (N-Terminus) - LS-C23749 from LifeSpan Bioscience
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Anti-GABRG2 Antibody (N-Terminus) - LS-C23748 from LifeSpan Bioscience
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