TJP2

Gene Symbol	TJP2
Entrez Gene	9414
Alt Symbol	C9DUPq21.11, DFNA51, DUP9q21.11, PFIC4, X104, ZO2
Species	Human
Gene Type	protein-coding
Description	tight junction protein 2
Other Description	Friedreich ataxia region gene X104 (tight junction protein ZO-2)|tight junction protein ZO-2|zona occludens 2|zonula occludens protein 2
Swissprots	Q5VXL0 A2A3H9 Q5VXL1 Q9UDY2 Q9UDY1 Q99839 B7Z7T6 B7Z2R8 F5H886 Q9UDY0 F5H301 Q8NI14 Q8N756 Q15883
Accessions	AAC02527 AAD20387 AAD56218 AAD56219 EAW62476 EAW62477 EAW62478 EAW62479 EAW62480 Q9UDY2 AA724570 AF083892 AAC33121 AF083893 AAC33122 AF489824 AAM28524 AI738923 AK025185 AK295016 BAH11949 AK295034 BAH11954 AK302483 BAH13722 AK304447 BAH14190 AK307697 AK308564 AM392689 CAL37567 AM392712 CAL37590 AM392803 CAL37681 AM392967 CAL37845 BC027592 AAH27592 BC028426 CX865985 DA270962 DB090695 DB196171 DC325189 L27476 AAA61300 U84581 AAB41794 XM_005252314 XP_005252371 XM_006717324 XP_006717387 XM_011519204 XP_011517506 XM_011519205 XP_011517507 XM_011519206 XP_011517508 XM_011519207 XP_011517509 XM_011519208 XP_011517510 XM_011519209 XP_011517511 NM_001170414 NP_001163885 NM_001170415 NP_001163886 NM_001170416 NP_001163887 NM_001170630 NP_001164101 NM_004817 NP_004808 NM_201629 NP_963923
Function	Plays a role in tight junctions and adherens junctions.
Subcellular Location	Cell junction, adherens junction. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Nucleus {ECO:0000250}. Note=Also nuclear under environmental stress conditions and in migratory endothelial cells and subconfluent epithelial cell cultures. {ECO:0000250}.
Tissue Specificity	This protein is found in epithelial cell junctions. Isoform A1 is abundant in the heart and brain. Detected in brain and skeletal muscle. It is present almost exclusively in normal tissues. Isoform C1 is expressed at high level in the kidney, pancreas, heart and placenta. Not detected in brain and skeletal muscle. Found in normal as well as in most neoplastic tissues. {ECO:0000269|PubMed:11018256}.
Top Pathways	Tight junction, Vibrio cholerae infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TJP2 protein fragment - ab160480 from Abcam Category Protein Source Wheat germ Species Human

TJP2 / ZO2 / ZO-2 Antibody Blocking Peptide - LS-E4683 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TJP2 / ZO2 / ZO-2 Antibody Blocking Peptide - LS-E15801 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TJP2 / ZO2 / ZO-2 Antibody Blocking Peptide - LS-E15802 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Tight Junction Protein 2 Protein - H00009414-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TJP2-Antibody-C-term-Blocking-Peptide - BP17049b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TJP2 Blocking Peptide - 33R-2642 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TJP2 Blocking Peptide - 33R-9376 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TJP2 - H00009414-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TJP2 - H00009414-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TJP2 fusion protein - Ag13577 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

TJP2 fusion protein - ag13534 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human TJP2, His-tagged - TJP2-3246H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Tight Junction Protein 2 (TJP2) - RPF167Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

ZO-2 (Q1112) Peptide - BS3192P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Tight Junction Protein 2 (TJP2) - RPF167Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Tight junction protein ZO-2(TJP2) ,partial - CSB-YP880071HU CSB-EP880071HU CSB-BP880071HU CSB-MP880071HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TJP2 (transcript variant 1) - TP305295 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Tight Junction Protein 2 Recombinant Protein Antigen - NBP1-86850PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Phospho-TJP2S978-Blocking-Peptide - BP3790a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

TJP2 Peptide, Human - M34GP15981H from Creative Peptides Category Peptide Source Synthetic. Species Human

TJP2 Recombinant Protein (OPCD07474) - OPCD07474 from Aviva Systems Biology Category Protein Source E.coli Species Human

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