MPK3

Gene Symbol MPK3
Entrez Gene 823706
Alt Symbol ATMAPK3, ATMPK3, T6D9.4, mitogen-activated protein kinase 3
Species Arabidopsis thaliana
Gene Type protein-coding
Description mitogen-activated protein kinase 3
Other Description -
Swissprots Q39023 Q9M1E3
Accessions AEE78054 CAB75493 Q39023 AF386961 AAK62406 AK226663 BAE98771 BT000007 AAN15326 NM_114433 NP_190150
Function Involved in oxidative stress-mediated signaling cascade (such as ozone). Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. May be involved in hypersensitive response (HR)-mediated signaling cascade by modulating LIP5 phosphorylation and subsequent multivesicular bodies (MVBs) trafficking. May phosphorylate regulators of WRKY transcription factors. Mediates the phosphorylation of VIP1 and subsequent stress genes transcription in response to Agrobacterium. MKK9-MPK3/MPK6 module phosphorylates and activates EIN3, leading to the promotion of EIN3-mediated transcription in ethylene signaling. MPK3/MPK6 cascade regulates camalexin synthesis through transcriptional regulation of the biosynthetic genes after pathogen infection. YDA-MKK4/MKK5-MPK3/MPK6 module regulates stomatal cell fate before the guard mother cell (GMC) is specified. This MAPK cascade also functions downstream of the ER receptor in regu
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15500467}. Nucleus {ECO:0000269|PubMed:15500467}. Note=Translocated into the nucleus in response to phosphorylation. {ECO:0000305}.
Top Pathways Plant-pathogen interaction

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