Gene Symbol | AKTIP |
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Entrez Gene | 64400 |
Alt Symbol | FT1, FTS |
Species | Human |
Gene Type | protein-coding |
Description | AKT interacting protein |
Other Description | AKT-interacting protein|fused toes homolog|fused toes protein homolog |
Swissprots | Q53H38 Q9H8T0 Q503B1 |
Accessions | CAD10180 EAW82803 EAW82804 EAW82805 EAW82806 EAW82807 EAW82808 EAW82809 Q9H8T0 AK023320 BAB14524 AK098222 AK222743 BAD96463 AK303503 BAG64536 AL133106 CAH56392 BC001134 AAH01134 BC095401 AAH95401 BG568989 BI545474 BM992149 CR457308 CAG33589 HQ448037 ADQ32518 XM_005256094 XP_005256151 XM_005256095 XP_005256152 XM_005256096 XP_005256153 XM_005256097 XP_005256154 XM_005256098 XP_005256155 NM_001012398 NP_001012398 NM_001308325 NP_001295254 NM_022476 NP_071921 |
Function | Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade. {ECO:0000269|PubMed:14749367, ECO:0000269|PubMed:18799622}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14749367}. Cell membrane {ECO:0000269|PubMed:14749367}; Peripheral membrane protein {ECO:0000269|PubMed:14749367}. |
FTS (K-14) - sc-241467 from Santa Cruz Biotechnology
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FTS (T-15) - sc-241466 from Santa Cruz Biotechnology
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FTS (KK-L5) - sc-134343 from Santa Cruz Biotechnology
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Anti-FTS antibody - ab56407 from Abcam
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Anti-FTS antibody - ab172671 from Abcam
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Anti-AKTIP / FTS Antibody - LS-C334581 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody (aa262-288, Biotin) - LS-C251165 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody (aa262-288, AP) - LS-C251163 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody (aa262-288, APC) - LS-C251164 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody (aa262-288, PE) - LS-C251168 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody (aa262-288, FITC) - LS-C251166 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody (aa262-288, Azide-free, HRP) - LS-C251167 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody - LS-C306191 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody (C-Terminus) - LS-C111836 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody - LS-C308034 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody (aa261-288) - LS-C319409 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody - LS-C341988 from LifeSpan Bioscience
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Anti-AKTIP / FTS Antibody (aa262-288) - LS-C157543 from LifeSpan Bioscience
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FTS Antibody - NBP1-53106 from Novus Biologicals
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FTS Antibody - NBP2-14279 from Novus Biologicals
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FTS Antibody - NBP2-14278 from Novus Biologicals
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FTS Antibody (2A11) - H00064400-M02 from Novus Biologicals
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FTS Antibody - H00064400-B01P from Novus Biologicals
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FTS Antibody - H00064400-B01 from Novus Biologicals
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FTS Antibody - H00064400-A01 from Novus Biologicals
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