PARL

Gene Symbol PARL
Entrez Gene 55486
Alt Symbol PRO2207, PSARL, PSARL1, PSENIP2, RHBDS1
Species Human
Gene Type protein-coding
Description presenilin associated, rhomboid-like
Other Description mitochondrial intramembrane cleaving protease PARL|mitochondrial intramembrane-cleaving protease PARL|presenilins-associated rhomboid-like protein, mitochondrial|rhomboid 7 homolog 1
Swissprots Q9BTJ6 Q9P1E3 Q96CQ4 Q9H300
Accessions CAD67638 CAI93557 CBF58125 CBF58133 CBF68751 CBF68759 CBU83560 CBU83568 CBU93625 CBU93633 EAW78311 EAW78312 Q9H300 AF197937 AAG28519 AK024765 BC003653 AAH03653 BC014058 AAH14058 CA417847 CB122278 DQ893442 ABM84368 DQ896749 ABM87748 XM_005247582 XP_005247639 XM_005247584 XP_005247641 XM_005247587 XP_005247644 NM_001037639 NP_001032728 NM_018622 NP_061092 NM_001037640
Function Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain. {ECO:0000250, ECO:0000269|PubMed:14732705, ECO:0000269|PubMed:17116872}.
Subcellular Location Mitochondrion inner membrane {ECO:0000269|PubMed:17116872}; Multi-pass membrane protein {ECO:0000269|PubMed:17116872}.

PARL (H-292) - sc-98994 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PARL (H-300): sc-98994. Western blot analysis of PARL expression in Jurkat whole cell lysate.

PARL (K-15) - sc-47312 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PARL (N-12) - sc-47313 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PARL (A-24) - sc-133884 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
PARL (A-24): sc-133884. Western blot analysis of PARL expression in COLO 320DM whole cell lysate.

Anti-PARL antibody - ab118554 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab118554 at 5&microg/ml staining PARL in Formalin-Fixed, Paraffin-Embedded Human pancreas tissue by immunohistochemistry.

Anti-PARL / PSARL Antibody (aa97-146) - LS-C80681 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PARL antibody LS-C80681 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-PARL / PSARL Antibody (clone 8C4B2;1H12E10) - LS-C108879 from LifeSpan Bioscience

Prices $320.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8C4B2;1H12E10
Western blot using PARL mouse monoclonal antibody against truncated Trx-PARL recombinant protein (1) and truncated MBP-PARL(aa112-167) recombinant protein (2).

Anti-PARL / PSARL Antibody (N-Terminus) IHC-plus™ - LS-B5095 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PARL antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5095 concentration 5 ug/ml.

Anti-PARL / PSARL Antibody (C-Terminus) - LS-C209359 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PARL Antibody - NBP1-59496 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PARL Antibody [NBP1-59496] - Sample Tissue: Human Jurkat Antibody Dilution: 1.0 ug/ml

PARL Antibody - AF7306 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal

PARL Antibody - NBP1-80878 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PARL Antibody - NBP1-76938 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PARL Antibody [NBP1-76938] - 3T3 cell lysate with PARL antibody at (A) 1 and (B) 2 ug/ml.

PARL Antibody - NBP1-44262 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PARL Antibody (8C4B2) - NBP1-51546 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8C4B2
Western Blot: PARL Antibody (8C4B2) [NBP1-51546] - Western blot analysis using PARL mouse mAb against truncated Trx-PARL recombinant protein (1) and truncated MBP-PARL(aa112-167) recombinant protein (2).

PARL Antibody (4F4) - H00055486-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F4

Monoclonal Anti-PSARL antibody produced in mouse - SAB1403289 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F4
<B>ELISA</B><BR/>Monoclonal Anti-PSARL: <B>Cat. No. SAB1403289</B>: Detection limit for recombinant GST tagged PARL is 1 ng/mL.

Anti-PARL antibody produced in rabbit - SAB3500322 from Sigma-Aldrich

Prices $348.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunocytochemistry</B><BR/>Anti-PARL: <B>Cat. No. SAB3500322</B>: Immunocytochemistry of PARL in 3T3 cells with PARL antibody at 2.5 μg/mL.

Monoclonal Anti-PARL antibody produced in mouse - SAB5300227 from Sigma-Aldrich

Prices $347.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8C4B2

Anti-PARL antibody produced in rabbit - HPA019545 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PARL: <B>Cat. No. HPA019545</B>: Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.

Anti-PARL antibody produced in rabbit - AV44851 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PARL: <B>Cat. No. AV44851</B>: Immunohistochemistry of PARL in Human Kidney tissue with PARL antibody at 4-8 μg/mL.

PARL Antibody (OAAD00266) - OAAD00266 from Aviva Systems Biology

Prices $290.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8C4B2;1H12E10

PARL antibody - N-terminal region (ARP44851_P050) - ARP44851_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ETV4-Antibody - AO1193a from Abgent, a WuXi AppTec company

Prices $385.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A2G3
Figure 1: Western blot analysis using ETV4 mouse mAb against K562 cell lysate (1).

PARL antibody - GTX85382 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-PARL antibody used in ICC/IF. GTX85382
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