PARL

Gene Symbol	PARL
Entrez Gene	55486
Alt Symbol	PRO2207, PSARL, PSARL1, PSENIP2, RHBDS1
Species	Human
Gene Type	protein-coding
Description	presenilin associated, rhomboid-like
Other Description	mitochondrial intramembrane cleaving protease PARL|mitochondrial intramembrane-cleaving protease PARL|presenilins-associated rhomboid-like protein, mitochondrial|rhomboid 7 homolog 1
Swissprots	Q9BTJ6 Q9P1E3 Q96CQ4 Q9H300
Accessions	CAD67638 CAI93557 CBF58125 CBF58133 CBF68751 CBF68759 CBU83560 CBU83568 CBU93625 CBU93633 EAW78311 EAW78312 Q9H300 AF197937 AAG28519 AK024765 BC003653 AAH03653 BC014058 AAH14058 CA417847 CB122278 DQ893442 ABM84368 DQ896749 ABM87748 XM_005247582 XP_005247639 XM_005247584 XP_005247641 XM_005247587 XP_005247644 NM_001037639 NP_001032728 NM_018622 NP_061092 NM_001037640
Function	Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain. {ECO:0000250, ECO:0000269|PubMed:14732705, ECO:0000269|PubMed:17116872}.
Subcellular Location	Mitochondrion inner membrane {ECO:0000269|PubMed:17116872}; Multi-pass membrane protein {ECO:0000269|PubMed:17116872}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PARL full length protein - ab153398 from Abcam Category Protein Source Wheat germ Species Human

Human PARL peptide - ab45230 from Abcam Category Peptide

Human PARL protein fragment - ab153399 from Abcam Category Protein Source Wheat germ Species Human

PARL / PSARL Antibody Blocking Peptide - LS-E16472 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PARL / PSARL Antibody Blocking Peptide - LS-E30555 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human PARL Protein - H00055486-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human PARL Protein - H00055486-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PARL Blocking Peptide - NBP1-76938PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

PARL Peptide - GTX85382-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

PARL Blocking Peptide - 33R-8594 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PARL - H00055486-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

PARL - H00055486-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PARL - H00055486-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PARL Control Peptide - AP30647CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

PARL Peptide - 4761P from ProSci Category Peptide Species Human

PARL Protein - abx163153 from Abbexa Category Protein Species Human

PARL Recombinant Protein Antigen - NBP1-80878PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PARL Peptide, Human - M34GP11309H from Creative Peptides Category Peptide Source Synthetic. Species Human

Presenilins-associated rhomboid-like protein (PARL), Recombinant Protein - MBS7025375 from MyBioSource Category Protein Prices $1,140.00, $2,125.00, $3,330.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

PARL fusion protein - Ag24789 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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