| Gene Symbol | B4GALT1 |
|---|---|
| Entrez Gene | 2683 |
| Alt Symbol | B4GAL-T1, CDG2D, GGTB2, GT1, GTB, beta4Gal-T1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| Other Description | UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1|UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1|beta-1,4-GalTase 1|beta-1,4-galactosyltransferase 1|glycoprotein-4-beta-galactosyltransferase 2|lactose synthase |
| Swissprots | Q12909 Q14523 Q14509 D3DRL2 P15291 B2R710 Q12911 Q14456 Q12910 |
| Accessions | AAB00776 CAT03462 EAW58520 EAW58521 P15291 A23697 CAA01685 AK296928 BAG59480 AK297541 BAG59940 AK312797 BAG35657 AK316294 BAH14665 AY864848 BC034244 BC035442 BC045773 AAH45773 BU624063 BX648438 D29805 BAA06188 HG765099 CDJ98631 HG765101 CDJ98633 M13701 AAA35935 M22921 AAA35936 U10472 AAA68218 U10473 AAA68219 U10474 AAA68220 X13223 CAA31611 X14085 CAA32247 X55415 CAA39073 XM_005251440 XP_005251497 NM_001497 NP_001488 |
| Function | The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. |
| Subcellular Location | Processed beta-1,4-galactosyltransferase 1: Secreted. Note=Soluble form found in body fluids. |
| Tissue Specificity | Ubiquitously expressed, but at very low levels in fetal and adult brain. |
| Top Pathways | N-Glycan biosynthesis, Other types of O-glycan biosynthesis, Glycosaminoglycan biosynthesis - keratan sulfate, Galactose metabolism, Glycosphingolipid biosynthesis - lacto and neolacto series |