PIWIL3

Gene Symbol	PIWIL3
Entrez Gene	440822
Alt Symbol	HIWI3
Species	Human
Gene Type	protein-coding
Description	piwi-like RNA-mediated gene silencing 3
Other Description	piwi-like 3|piwi-like protein 3
Swissprots	Q7Z3Z3
Accessions	EAW59679 Q7Z3Z3 AB079368 BAC81343 AK302409 BAG63719 AK315806 BC144693 BC144696 BC167797 AAI67797 NM_001008496 NP_001008496 NM_001255975 NP_001242904 NR_045648 NR_045649
Function	May play a role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm. Note=Probable component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. {ECO:0000250}.
Tissue Specificity	Expressed in testis. {ECO:0000269|PubMed:12906857}.
Top Pathways	Dorso-ventral axis formation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PIWIL3 peptide - ab39467 from Abcam Category Peptide

PIWIL3 Antibody Blocking Peptide - LS-E31024 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PIWIL3 Blocking Peptide - NBP1-76490PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

PIWIL3 Peptide - GTX85145-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

PIWIL3 control peptide - AP26293CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

PIWI-L3 Peptide - 6033P from ProSci Category Peptide Species Human

Recombinant Human Piwi-like protein 3(PIWIL3) ,partial - CSB-YP773785HU CSB-EP773785HU CSB-BP773785HU CSB-MP773785HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Piwi-like protein 3 (PIWIL3), partial, Recombinant Protein - MBS1404314 from MyBioSource Category Protein Prices $1,040.00, $1,040.00, $1,270.00, $1,270.00, $1,560.00, $1,560.00, $2,020.00, $2,020.00, $2,020.00, $3,005.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PIWIL3 Protein - NBP2-31855PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

PIWIL3 Peptide, Human - M34GP11830H from Creative Peptides Category Peptide Source Synthetic. Species Human

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