| Gene Symbol |
CENPL
|
| Entrez Gene |
91687
|
| Alt Symbol |
C1orf155, CENP-L, dJ383J4.3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
centromere protein L
|
| Other Description |
interphase centromere complex protein 33
|
| Swissprots |
Q8N0S6 Q5TEL5 Q96ND4
|
| Accessions |
EAW90956 EAW90957 EAW90958 EAW90959 Q8N0S6 AK055606 BAB70968 AK056348 BAB71159 BC007071 AAH07071 BC007923 BC019022 BC033154 AAH33154 BC066658 AAH66658 DA173140 DA472686 DB244459 DN995099 HQ447714 ADQ32199 NM_001127181 NP_001120653 NM_001171182 NP_001164653 NM_033319 NP_201576
|
| Function |
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. {ECO:0000269|PubMed:16716197}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:16716197}. Chromosome, centromere {ECO:0000269|PubMed:16716197}. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
|
![Western Blot: CENPL Overexpression Lysate (Adult Normal) [NBL1-09087] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CENPL.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6325_CENPL%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09087-img0002.jpg)