Gene Symbol | CENPL |
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Entrez Gene | 91687 |
Alt Symbol | C1orf155, CENP-L, dJ383J4.3 |
Species | Human |
Gene Type | protein-coding |
Description | centromere protein L |
Other Description | interphase centromere complex protein 33 |
Swissprots | Q8N0S6 Q5TEL5 Q96ND4 |
Accessions | EAW90956 EAW90957 EAW90958 EAW90959 Q8N0S6 AK055606 BAB70968 AK056348 BAB71159 BC007071 AAH07071 BC007923 BC019022 BC033154 AAH33154 BC066658 AAH66658 DA173140 DA472686 DB244459 DN995099 HQ447714 ADQ32199 NM_001127181 NP_001120653 NM_001171182 NP_001164653 NM_033319 NP_201576 |
Function | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. {ECO:0000269|PubMed:16716197}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16716197}. Chromosome, centromere {ECO:0000269|PubMed:16716197}. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex. |
CENP-L CRISPR/Cas9 KO Plasmid (h) - sc-413909 from Santa Cruz Biotechnology
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CENP-L HDR Plasmid (h) - sc-413909-HDR from Santa Cruz Biotechnology
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CENP-L Double Nickase Plasmid (h) - sc-413909-NIC from Santa Cruz Biotechnology
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CENP-L Double Nickase Plasmid (h2) - sc-413909-NIC-2 from Santa Cruz Biotechnology
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CENP-L CRISPR Activation Plasmid (h) - sc-413909-ACT from Santa Cruz Biotechnology
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CENP-L CRISPR Activation Plasmid (h2) - sc-413909-ACT-2 from Santa Cruz Biotechnology
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CENP-L Lentiviral Activation Particles (h) - sc-413909-LAC from Santa Cruz Biotechnology
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CENP-L Lentiviral Activation Particles (h2) - sc-413909-LAC-2 from Santa Cruz Biotechnology
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CENP-L siRNA (h) - sc-78992 from Santa Cruz Biotechnology
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CENP-L shRNA Plasmid (h) - sc-78992-SH from Santa Cruz Biotechnology
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CENP-L shRNA (h) Lentiviral Particles - sc-78992-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU067521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5947 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5947 from Sigma-Aldrich
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CENPL siRNA (Human) - CRJ4067 from Cohesion Biosciences
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CENPL - MBS8230956 from MyBioSource
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shRNA set against Human CENPL (NM_033319.3) - SHH261685 from Creative biogene
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Human CENPL siRNA - orb274568 from Biorbyt
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CENPL shRNA Plasmid (Human) - CHJ4067 from Cohesion Biosciences
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CENPL miRNA 3'UTR clone - MiUTR3H-11934 from Creative biogene
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CENPL miRNA 3'UTR clone - MiUTR3H-11935 from Creative biogene
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