Gene Symbol | HCFC1R1 |
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Entrez Gene | 54985 |
Alt Symbol | HPIP |
Species | Human |
Gene Type | protein-coding |
Description | host cell factor C1 regulator 1 (XPO1 dependent) |
Other Description | HCF-1 beta-propeller-interacting protein|host cell factor C1 regulator 1 |
Swissprots | Q68EN7 D3DUA7 Q9NWW0 |
Accessions | CAV30734 CAV30735 CAV30736 EAW85424 EAW85425 EAW85426 EAW85427 Q9NWW0 AK000575 BAA91265 AK293768 BAG57184 AY116892 AAM49798 BC064026 AAH64026 BC065514 BC080178 AAH80178 BM790570 BM925785 BU623445 BU633901 CN427571 CR457245 CAG33526 HQ447528 ADQ32014 XM_011522558 XP_011520860 XM_011522559 XP_011520861 NM_001002017 NP_001002017 NM_001002018 NP_001002018 NM_001288665 NP_001275594 NM_001288666 NP_001275595 NM_001288667 NP_001275596 NM_001288668 NP_001275597 NM_001308070 NP_001294999 NM_017885 NP_060355 |
Function | Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus. {ECO:0000269|PubMed:12235138}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12235138}. Nucleus {ECO:0000269|PubMed:12235138}. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:12235138}. |
HCFC1R1 (C-12) - sc-164570 from Santa Cruz Biotechnology
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Anti-Host cell factor C1 regulator 1 antibody - N-terminal - ab170514 from Abcam
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Anti-HCFC1R1 / HPIP Antibody (aa1-30, AP) - LS-C236123 from LifeSpan Bioscience
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Anti-HCFC1R1 / HPIP Antibody (aa1-30, APC) - LS-C236124 from LifeSpan Bioscience
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Anti-HCFC1R1 / HPIP Antibody (aa1-30, Biotin) - LS-C236126 from LifeSpan Bioscience
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Anti-HCFC1R1 / HPIP Antibody (aa1-30, FITC) - LS-C236127 from LifeSpan Bioscience
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Anti-HCFC1R1 / HPIP Antibody (aa1-30, PE) - LS-C236128 from LifeSpan Bioscience
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Anti-HCFC1R1 / HPIP Antibody (aa1-30, Azide-free, HRP) - LS-C249167 from LifeSpan Bioscience
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Anti-HCFC1R1 / HPIP Antibody (aa1-30) - LS-C321890 from LifeSpan Bioscience
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Anti-HCFC1R1 / HPIP Antibody (aa35-84) - LS-C111821 from LifeSpan Bioscience
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Anti-HCFC1R1 / HPIP Antibody (aa1-30) - LS-C166808 from LifeSpan Bioscience
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HCFC1R1 Antibody - NBP2-31788 from Novus Biologicals
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HCFC1R1 Antibody - NBP1-53070 from Novus Biologicals
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ANTI-HCFC1R1 (N-TERM) antibody produced in rabbit - SAB1303493 from Sigma-Aldrich
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Anti-HCFC1R1 antibody produced in rabbit - SAB2104280 from Sigma-Aldrich
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Anti-HCFC1R1 antibody produced in rabbit - HPA059647 from Sigma-Aldrich
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HCFC1R1 antibody - middle region (ARP56149_P050) - ARP56149_P050 from Aviva Systems Biology
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HCFC1R1-Antibody-N-term - AP11644a from Abgent, a WuXi AppTec company
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HCFC1R1 antibody, Internal - GTX45103 from GeneTex
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HCFC1R1 Antibody - N-terminal region (OAAB07890) - OAAB07890 from Aviva Systems Biology
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Anti -HCFC1R1, NT (HCFC1R1, HPIP, Host cell factor C1 regulator 1, HCF-1beta-propeller-interacting protein) - 036455 from USBiological Life Science
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Anti -HCFC1R1, NT (HCFC1R1, HPIP, Host cell factor C1 regulator 1, HCF-1beta-propeller-interacting protein) (AP) - 036455-AP from USBiological Life Science
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Anti -HCFC1R1, NT (HCFC1R1, HPIP, Host cell factor C1 regulator 1, HCF-1beta-propeller-interacting protein) (APC) - 036455-APC from USBiological Life Science
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Anti -HCFC1R1, NT (HCFC1R1, HPIP, Host cell factor C1 regulator 1, HCF-1beta-propeller-interacting protein) (Azide free) (HRP) - 036455-HRP from USBiological Life Science
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Anti -HCFC1R1, NT (HCFC1R1, HPIP, Host cell factor C1 regulator 1, HCF-1beta-propeller-interacting protein) (Biotin) - 036455-Biotin from USBiological Life Science
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